Results 101 to 110 of about 4,092,098 (300)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Quality management systems in radiology

open access: yesSouth African Journal of Radiology, 2013
Background: The use of X-ray imaging is ever increasing in proportion to the need for radiological services and technological capabilities. Quality management that includes patient radiation dose monitoring is fundamental to safety and quality ...
Geoffrey K. Korir   +4 more
doaj   +1 more source

Quality Management and Innovation in Information Services - The case study of the Documentation Services of the University of Minho [PDF]

open access: yes, 2008
[The present paper is based on a curricular traineeship, part of the Degree in Information Science, under the theme of the implementation of Quality Management Systems, occurred at the Documentation Services of the University of Minho (SDUM).] The SDUM ...
Guedes, Susana
core  

Implementing quality management systems to close the AI translation gap and facilitate safe, ethical, and effective health AI solutions. [PDF]

open access: yesNPJ Digit Med, 2023
Overgaard SM   +6 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Adaptive Design of Spindle Machine Tool

open access: yesJournal of Mechanical Engineering
Article describes the development of an application for generating 3D models of bearings used in the design of machine tool spindles. The models are created in CATIA v5 software using parametric modelling, which allows for easy modification of bearing ...
Hošták Peter, Šooš Ľubomír
doaj   +1 more source

Strategies to improve quality and safety and reduce cost of peroduction in organic and low-input crop production systems [PDF]

open access: yes, 2009
Organic crop production seeks to produce high quality foods while reducing the inputs in order to promote environmental quality and conserve resources. This necessitates optimal production systems in terms of soil fertility and plant health.
Lucius, Tamm
core  

Factor Analysis of Quality Management Systems Implementation in Healthcare: An Online Survey. [PDF]

open access: yesHealthcare (Basel), 2022
Rawshdeh M   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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