Results 81 to 90 of about 986,010 (247)
Integrated Management Systems-Quality, Environment and Safety
, 2002 The implementation of management systems such as the qualrty, environmental and occupational health and safety management systems to the national and/or intemational standards ISO 9000, ISO 14000 and AS/NZS 4801 has been well researched and studied in ...
Akpolat, H, Xu, J
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Increasing the value of quality management systems
, 2019 Over one million organisations have a Quality Management System (QMS) certified to the ISO9000 standard; however, the system requires a lot of resources and its value has been questioned. The purpose of this paper is to investigate how different types of
Elg, Mattias, +3 more
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BMC Health Services Research, 2016 Background As primary health care (PHC) centers in Saudi Arabia provide standardized preventive and curative oral health care (OHC) services, challenges remain. In addition, evidence of determinants of OHC seeking behavior is unknown.
Abeer Al-Jaber, Omar B. Da’ar
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Translating transparency under pressure—openness and consistency in Swedish election administration
Frontiers in Political ScienceTransparency is a celebrated ideal in public administration, yet a complex ideal, as it keeps coming back in different shapes and for different purposes.
Ida Nilsing
doaj +1 more source
Implementation of the ISO 9001 quality management system - process, impact and benefits
Vojnotehnički Glasnik, 2013 Modern business is characterized by greater and greater market competition through all business areas and all activities. Establishment of market positions is a very important element of business activities in every organization.
Aleksandar Ž. Drenovac +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
BMJ Open QualityBackground Healthcare organisations strive to meet their current and future challenges and need to increase their capacity for continuous organisational improvement and learning (COIL).
Ninni Löfqvist
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source