Results 151 to 160 of about 180,214 (308)

Divergence of risk indicators and the conditions for market discipline in banking [PDF]

Accurate measurement of bank risk is a matter of considerable importance for bank regulation and supervision. Current practices in most countries emphasize reliance on financial statement data for assessing banks’ risk.
Jens Forssbaeck
core  

Patient benefit from seamless implant monitoring

Zdravniški Vestnik, 2005
Background: Patients with electrostimulation devices visit the hospital regularly for follow-up. The workload of out-patient departments is ever increasing, but a less frequent check-up is unwanted, as it could impair reliability and effectiveness of the
Karsten Wallbrück, Jürgen Schrader
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Development of pH Indicator Composite Films Based on Anthocyanins and Neutral Red for Monitoring Minced Meat and Fish in Modified Gas Atmosphere (MAP)

Fresh meat and fish are widely consumed foods with short and very short shelf lives, respectively. Efficient supply chains and the judicious use of food packaging are the most effective means of extending shelf life and thus reducing food waste and ...
Heloisa N. Bordallo, Blennow, Andreas, Bordallo, Heloisa N., Jacob Judas Kain Kirkensgaard, Marwa Faisal, Lene Meineret, Ulvskov, Peter, Kirkensgaard, Jacob Judas Kain, Tomas Jacobson, Faisal, Marwa, Andreas Blennow, Peter Ulvskov, Jacobson, Tomas, Meineret, Lene, Peter Vorup, Vorup, Peter   +15 more
core   +1 more source

Implementation of a Dynamic LoRa Network for Real-Time Monitoring of Water Quality

Designs
Water quality is a key factor in environmental and agronomic sustainability. Due to the influence of human activity and industrial development, the composition of rivers or lakes can experience significant variations both immediately and over time.
Kevin Joel Berrio Quintanilla, Pamela Lorena Huayta Cosi, Jorge Leonardo Huarca Quispe, Juan Carlos Cutipa Luque, Juan Pablo Julca Avila   +4 more
doaj   +1 more source

Monitoring air quality indicators and energy consumption in Dalarnas Villa during operation of a demand-controlled exhaust ventilation system

, 2020
A real-world study was undertaken of the indoor air quality in a recently-built single family home in central Sweden, to establish whether demand controlled ventilation provided superior interior conditions, when compared with other air supply strategies, including the standard used by the Swedish buildings regulator.
Garman, Ian, Haj Ahmad, Ahmad
openaire   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Modeling and Monitoring Subsurface Water Quality Indicators of Sistan Plain using Geographic Information Systems

محیط زیست و مهندسی آب, 2019
Investigating the spatial variation of groundwater quality parameters is important in identifying the quality of the aquifer and contaminating resources, and determining the most appropriate management solutions. Geostatistical and GIS methods can be useful tools in this regard.
openaire   +1 more source