Results 141 to 150 of about 872,117 (284)

Monitoring of Spatial Data Infraestructures

, 2010
SDI monitoring and evaluation is increasingly attracting the attention of both public sector bureaucrats seeking justification for providing public sources to SDI and SDI practitioners requiring a measure of success of their SDI strategy.
Castelein, Watse, Manso Callejo, Miguel Ángel   +1 more
core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Implementation of a Dynamic LoRa Network for Real-Time Monitoring of Water Quality

Designs
Water quality is a key factor in environmental and agronomic sustainability. Due to the influence of human activity and industrial development, the composition of rivers or lakes can experience significant variations both immediately and over time.
Kevin Joel Berrio Quintanilla, Pamela Lorena Huayta Cosi, Jorge Leonardo Huarca Quispe, Juan Carlos Cutipa Luque, Juan Pablo Julca Avila   +4 more
doaj   +1 more source

Evaluation of Monitoring Programs For the NHEP Monitoring Plan [PDF]

, 2002
The objective of this report is to evaluate the monitoring programs for indicators in the NHEP Monitoring Plan (NHEP, 2002) to determine if sufficient data are being collected for each indicator and to identify any datagaps. The outcome of this report is
Trowbridge, Phil
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developing ecosystem service indicators: experiences and lessons learned from sub-global assessments and other initiatives [PDF]

, 2011
People depend upon ecosystems to supply a range of services necessary for their survival and well-being. Ecosystem service indicators are critical for knowing whether or not these essential services are being maintained and used in a sustainable manner ...
Armenteras, Dolors, Ash, Neville, Barano, Thomas, Beltrame, Coralie, Berg, Hakan, Bhagabati, Nirmal, Biala, Katarzyna, Birge, Traci, Bondarev, Alexander, Brown, Claire, Butchart, Stuart, Davidson, Nick, De Groot, Rudolf, Doswald, Natalie, Díaz, Sandra, Espaldon, Maria Victoria, Fuentes, Rodrigo, Garcia, Keisha, Ghate, Utkarsh, Girvan, Alexander, Goethals, Peter, Hadian, Oki, Höft, Robert, Koleff, Patricia, Kumar, Chetan, Larigauderie, Anne, Lasco, Rodel, Layke, Christian, Linstead, Conor, Luque Panadero, Victoria Eugenia, Mainka, Sue, Mapendembe, Abisha, Marcela, Mónica, Nybo, Signe, O'Farell, Patrick, Reyers, Belinda, Ricketts, Taylor, Ringold, Paul, Rodríguez Rodríguez, Davíd, Rosenthal, Amy, Sandlund, Odd Terje, Sarukhán, José, Scharlemann, Jorn, Schlatter, Christian, Simpson, Lucy, Stott, Andrew, Tierney, Megan, Tyrell, Tristan, UNEP-WCMC, -, Urquiza, Tania, Vackár, David, van Oudenhoven, Alexander, Viglizzo, Ernesto, Walpole, Matt, Watts, Jim, Williams, James, Yashina, Tatyana, Zandri, Edoardo   +57 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

From Indicators to Insights: Measuring Urban Quality of Life in Medium-Sized Greek Cities with the DPRD-20 Urban Indicator System

European Journal of Geography
Urban Quality of Life (UQoL) is a critical concept in urban studies, capturing the well-being of city residents through environmental, social, and economic conditions. This study refines the existing DPRD-50 system—originally developed to assess UQoL in
Eva Psatha
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source