Results 121 to 130 of about 180,214 (308)

Developing sensitive quality indicators for ground inter-hospital transport of adult critically ill patients using Donabedian model

Frontiers in Public Health
BackgroundThe complexity of inter-hospital transport (IHT) for critically ill patients poses challenges to quality evaluation. Currently, sensitive quality indicators for the entire process of IHT remain lacking. The objective of this study is to develop
Qianqian Zhang, Ge Zang, Naifu Tang, Li Zhang, Manman Yin, Tongtong Zhang, Bo Li, Bo Li   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Providing management system audit HSE-MS pattern for printing using ANP and DEMATEL model with emphasis on assessment methods of D & S and MISHA and OGP

Salāmat-i kār-i Īrān, 2015
Background and aims: one of the most important elements in the HSE-MS quality management system is “Audit”. Audit is the conformity of the subject with the standard requirements and regulations.
Sh Vosoughi, T Dana, N Serajzadeh
doaj  

Construction of a Technological Security Risk Monitoring and Early Warning System

中国工程科学
The technological revolution under geopolitics has intensified the risks of China’s scientific and technological security. Building a risk monitoring and early warning system in the field of scientific and technological security is of great significance ...
Liu Xiaofeng , Hu Gaoqiang , Fan Zhaoyuan , Sui Xiufeng   +3 more
doaj   +1 more source

Establishment and Implementation of Sponge City Monitoring System— A Case Study of Zhenjiang

Renmin Zhujiang, 2022
In order to effectively deal with urban water pollution and waterlogging,China proposes the concept of sponge city for stormwater management,which takes the control rate of total annual runoff,urban non-point pollution control,and urban rainstorm and ...
WANG Yan, YU Meixiu, LU Zhicong
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Fecal contamination of drinking-water in low- and middle-income countries: a systematic review and meta-analysis

, 2014
Background: access to safe drinking-water is a fundamental requirement for good health and is also a human right. Global access to safe drinking-water is monitored by WHO and UNICEF using as an indicator “use of an improved source,” which does not ...
Bain, R, Ryan Cronk (560336), Jim Wright (560337), Bain, R., Jamie Bartram (359970), Bartram, J., Yang, H, Hong Yang, Bartram, J, Cronk, R, Yang, Hong, Bartram, Jamie, Tom Slaymaker, Slaymaker, Tom, Wright, J.A., Slaymaker, T., Ryan Cronk, Robert Bain (560335), Cronk, Ryan, Bain, Robert, Hong Yang (37298), Jim Wright, Tom Slaymaker (560338), Wright, Jim, Wright, J, Slaymaker, T, Cronk, R., Jamie Bartram, Robert Bain   +28 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Selection of Practical Indicator Systems for Monitoring the Virological Quality of Potable Water, Wastewater, Solid Waste, Shellfish, Fish and Crops

Water Science and Technology, 1983
The actual detection of viruses or the use of an indicator system or systems to assess the presence of pathogenic viruses in contaminated environments is essential for the protection of human health. Herein are considered the possible surrogate relationships between pathogenic viruses and bacterial indicators of fecal pollution in the diverse ...
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source