Results 111 to 120 of about 24,703,824 (298)

Providing management system audit HSE-MS pattern for printing using ANP and DEMATEL model with emphasis on assessment methods of D & S and MISHA and OGP

open access: yesSalāmat-i kār-i Īrān, 2015
Background and aims: one of the most important elements in the HSE-MS quality management system is “Audit”. Audit is the conformity of the subject with the standard requirements and regulations.
Sh Vosoughi, T Dana, N Serajzadeh
doaj  

Smart Packaging System with Betalains and Rosemary Essential Oil to Extend Food Shelf Life and Monitor Quality During Storage

open access: yesPolysaccharides
Smart packaging is an alternative that may not only replace plastic containers, but also enable food quality monitoring. In this study, an innovative packaging system was developed using a starch-chitosan polymer matrix, infused with rosemary essential ...
Noemi Takebayashi-Caballero   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Developing sensitive quality indicators for ground inter-hospital transport of adult critically ill patients using Donabedian model

open access: yesFrontiers in Public Health
BackgroundThe complexity of inter-hospital transport (IHT) for critically ill patients poses challenges to quality evaluation. Currently, sensitive quality indicators for the entire process of IHT remain lacking. The objective of this study is to develop
Qianqian Zhang   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Challenge of Building Proper Urban Indicator System: A Proposal for Croatian Cities [PDF]

open access: yes
In this paper, urban indicator system is investigated in the context of urban policy processes. Indicators are seen as a tool to enhance urban management and special attention is given to their role in providing assistance in monitoring municipal ...
Zeljka Kordej De Villa   +1 more
core  

Construction of a Technological Security Risk Monitoring and Early Warning System

open access: yes中国工程科学
The technological revolution under geopolitics has intensified the risks of China’s scientific and technological security. Building a risk monitoring and early warning system in the field of scientific and technological security is of great significance ...
Liu Xiaofeng   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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