Results 101 to 110 of about 872,117 (284)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Smart Packaging System with Betalains and Rosemary Essential Oil to Extend Food Shelf Life and Monitor Quality During Storage

open access: yesPolysaccharides
Smart packaging is an alternative that may not only replace plastic containers, but also enable food quality monitoring. In this study, an innovative packaging system was developed using a starch-chitosan polymer matrix, infused with rosemary essential ...
Noemi Takebayashi-Caballero   +7 more
doaj   +1 more source

Evaluation of Effects of Wastewater Treatment Discharge on Estuarine Water Quality [PDF]

open access: yes, 2003
This report marks the completion of a two-year project focused on observed and estimated effects of wastewater treatment facilities (WWTFs) on estuarine water quality within the New Hampshire (NH) Seacoast region.
Bolster, Carl H.   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Developing sensitive quality indicators for ground inter-hospital transport of adult critically ill patients using Donabedian model

open access: yesFrontiers in Public Health
BackgroundThe complexity of inter-hospital transport (IHT) for critically ill patients poses challenges to quality evaluation. Currently, sensitive quality indicators for the entire process of IHT remain lacking. The objective of this study is to develop
Qianqian Zhang   +7 more
doaj   +1 more source

Comparing modified biological monitoring working party score system and several biological indices based on macroinvertebrates for water-quality assessment

open access: yesLimnologica, 2005
AbstractMacroinvertebrate communities from the lower Nysa Kłodzka River catchment, southern Poland, were analyzed seasonally, in order to assess changes in their composition and structure, in relation to water quality. Two major groups of sites, differing in both morphological structure and taxonomical composition by cluster analysis, were identified ...
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Providing management system audit HSE-MS pattern for printing using ANP and DEMATEL model with emphasis on assessment methods of D & S and MISHA and OGP

open access: yesSalāmat-i kār-i Īrān, 2015
Background and aims: one of the most important elements in the HSE-MS quality management system is “Audit”. Audit is the conformity of the subject with the standard requirements and regulations.
Sh Vosoughi, T Dana, N Serajzadeh
doaj  

Construction of a Technological Security Risk Monitoring and Early Warning System

open access: yes中国工程科学
The technological revolution under geopolitics has intensified the risks of China’s scientific and technological security. Building a risk monitoring and early warning system in the field of scientific and technological security is of great significance ...
Liu Xiaofeng   +3 more
doaj   +1 more source

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