Results 81 to 90 of about 24,703,824 (298)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A novel simultaneous monitoring method for surface roughness and tool wear in milling process

open access: yesScientific Reports
Quality prediction and condition monitoring are crucial for realizing zero-defect intelligent manufacturing. Surface roughness is an important technical indicator to measure the surface quality of parts.
Ruilin Liu, Wenwen Tian
doaj   +1 more source

SUBSYSTEM FOR MONITORING ATMOSPHERIC AIR QUALITY IN THE CYBER-PHYSICAL SYSTEM "SMART CITY"

open access: yesКомпютерні системи та інформаційні технології
The task of designing and developing a cyber-physical system "Smart City" is currently relevant for Ukraine. This study is devoted to the development of a method and subsystem for monitoring atmospheric air quality in the cyber-physical system "Smart ...
Tetiana HOVORUSHCHENKO   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

INDICATION OF THE CONDITION OF VEGETATION IN MAGNITOGORSK FOR ASSESSING THE QUALITY OF ATMOSPHERIC AIR AND IMPROVING ITS MONITORING SYSTEM

open access: yesГеографический вестник = Geographical bulletin
In 2016, specialists from the research institute UralNII Ecology conducted a scientific experiment in Magnitogorsk to assess the impact of atmospheric air pollution on vegetation in different parts of the city. The purpose of the study was to assess the condition of vegetation in different areas by measuring chlorophyll fluorescence and carotenoid ...
Irina P. Oputina   +2 more
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Quality Assurance Indicators of Long-Term Care in European Countries. ENEPRI Research Report No. 110, April 2012 [PDF]

open access: yes, 2012
This study reports on the quality indicators that were collected by the ANCIEN project partners in each country considered in Work Package 5 (Quality in Long-Term Care).
Casanova, Georgia, Dandi, Roberto
core  

Water Quality Program and Assessment Summary

open access: yes, 2002
This document provides context for the 2002 Texas Water Quality Inventory Waller Creek data sheetWaller Creek Working ...
Surface Water Quality Monitoring Program
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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