Results 81 to 90 of about 180,214 (308)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
SSM - Health SystemsPurpose: Emergency referral systems are vital to robust and resilient health systems, however, referral system strengthening efforts have been fragmented, often narrowly focused and lacking a clear measurement approach. We aimed to design a comprehensive
Megan M. Lydon +4 more
doaj +1 more source
National curriculum assessment in England: “Driving up standards”?
Revue Internationale d’Éducation de Sèvres, 2019 Notwithstanding the acknowledged importance of other outcomes of schooling, the quality of England’s education system is considered by its national politicians to be reflected primarily in students’ standards of academic attainment, with PISA survey ...
Sandra Johnson
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
European Biodiversity Observation Network: D1.1 The Selection of Biodiversity indicators for EBONE Development Work [PDF]
, 2010 The main aim of this report is to assess which biodiversity indicators should be selected as the basis for developing new EBONE methodologies for assessing biodiversity.
Jongman, R.H.G. +3 more
core
Revue Internationale d’Éducation de Sèvres, 2019 Notwithstanding the acknowledged importance of other outcomes of schooling, the quality of England’s education system is considered by its national politicians to be reflected primarily in students’ standards of academic attainment, with PISA survey ...
Sandra Johnson
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Field-scale validation of an automated soil nitrate extraction and measurement system
, 2009 One of the many gaps that needs to be solved by precision agriculture technologies is the availability of an economic, automated, on-the-go mapping system that can be used to obtain intensive and accurate ‘real-time’ data on the levels of nitrate ...
Astatkie, T. +5 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source