Results 41 to 50 of about 617,867 (260)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

COVID-19 pandemic anxiety, academic stress, and quality of life among college students in the Philippines: A mediation study

Cakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2023
Cognizant of the specific pathways that students' lives can be impacted by the Coronavirus Disease 2019 (COVID-19) pandemic, this study investigated the relationship between COVID-19 pandemic anxiety and quality of life of Filipino college students and ...
Jerome V. Cleofas, Ian Christopher N. Rocha, Rey G. Parcon   +2 more
doaj   +1 more source

Student Quality-of-Life in Academic Culture Perspective

JOMSIGN: Journal of Multicultural Studies in Guidance and Counseling, 2018
Quality of life is a study of human happiness, strength and life satisfaction for the better life. Quality of life as an important aspect in the development and lives of individuals known to correlate with various factors, but have not revealed many factors related to culture, especially in Indonesia.
openaire   +3 more sources

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Quality of life and academic productivity among faculty members in health colleges

Discover Psychology
Faculty QoL is increasingly recognized as a key component of effective higher-education systems, particularly in health-science institutions where academic, clinical, and administrative roles overlap.
Ali Alattas, Khaled Almisnid, Ahmaed Baashar, Mohamed Eldigire Ahmed   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Future Anxiety and its Relationship to Academic Self-efficacy among University Female Students in Saudi Arabia [PDF]

Maǧallaẗ Kulliyyaẗ Al-Tarbiyyẗ Ǧamiʿaẗ Banhā
The present study sought to explore future anxiety and its relationship to academic self-efficacy among a sample of university female students at an academic institution in Saudi Arabia.
نوره عبدالرحمن المطرفي
doaj   +1 more source

The relationship between the quality of life of medical students and their academic performance

Hygiene and sanitation, 2022
Introduction. According to modern literature data, the quality of life of medical students is significantly lower than in the general population. Poor quality of life affects academic performance and can lead to rapid burnout. In this regard, an urgent problem is to study the practical significance of the impact of academic performance on the quality ...
Zarnigar F. Gumbatova, Alfiya I. Aminova, Tatyana Yu. Eryushova, Susanna A. Guseva, Ekaterina I. Belova, Albina S. Pestova, Marina A. Manina   +6 more
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source