Results 61 to 70 of about 617,867 (260)

The mediating role of academic achievement on the relationship between core self-evaluations and quality of Life

مجله علوم روانشناختی, 2017
Quality of life is a degree of success that is felt by individuals or groups of people. Personality is a fundamental components in predicting quality of life and there is a mutual relationships between quality of life and academic motivation in ...
Mohtaram Nemat Tavousi
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effects of a combined training program on lipid metabolism metabolic syndrome and physical fitness in perimenopausal Chinese female teachers

Scientific Reports
Metabolic syndrome (MetS), which affects over 24% of Chinese adults [4], poses a particular risk to sedentary occupations such as university faculty.
HongTao Xia, Kun Du, Dan Sang, HongYong Jung, Suting Xi   +4 more
doaj   +1 more source

The quality of working life of academics: A scoping review

Journal of Comparative Research in Anthropology and Sociology, 2023
This article aims to explore the scientific literature on the quality of the working life of university teachers. For this purpose, a scoping review methodology was used, which involved the systematic search of articles by relevant words on five databases. The theoretical perspective is the Theory of Duality of Technology formulated by Orlikowski (1992)
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Navigating workaholism, life balance, and quality of life among academic nurse educators: exploring the role of resilience

BMC Nursing
Background Academic nurse educators play a vital role in shaping the future nursing workforce. However, the high demands of their profession often contribute to workaholism—an uncontrollable compulsion to work excessively—which disrupts work-life balance
Ebtsam Aly Abou Hashish, Hala Ahmed Abdou, Noura Mohamed Fadl Abdel Razek   +2 more
doaj   +1 more source

The Relationship of Academic Achievement Motivation with Emotional Intelligence and Quality of Life of University Students [PDF]

پژوهش‌های سلامت‌محور, 2017
Background & Objectives: Today, studies have shown the impact of emotional intelligence and quality of life on academic achievement motivation. Paying attention to the factors that lead to academic motivation is very important.
Rahil Ghorbani Nia, Fatemeh Izadi
doaj  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The relationship between health-related quality of life and academic success in nursing students: the mediating role of academic burnout and academic motivation

BMC Medical Education
Background The identification of the key factors that affect academic success in nursing students, including health-related quality of life, academic burnout, and academic motivation, has been of the utmost importance to date.
Fatemeh Torkani, Seyed-Hasan Ahmadi, Alireza Binazir, Marjan Moradi Fath, Navid Shafigh, Hanieh Asadiparvar-Masouleh, Parvaneh Vasli   +6 more
doaj   +1 more source