Results 141 to 150 of about 5,811,138 (314)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Journal of Advances in Medical Education and Professionalism, 2015 Introduction: In the design of educational programs, much attention has been paid to teaching methods, needs assessment, an important part of the development of educational programs, generally is neglected.
JAVAD KOJURI +7 more
doaj
Assessment of Quality of Education in the Case of Bahir Dar Health Science College, Northwest Ethiopia:- A Mixed Method Approach. [PDF]
Adv Med Educ Pract, 2023 Zemariam AB +4 more
europepmc +1 more source
Improving the Quality of Education Through Quality of Service and Education Costs
Nidhomul Haq : Jurnal Manajemen Pendidikan IslamThe quality of education is a key measure of an educational institution's ability to produce high-achieving students. Such institutions must provide effective learning services and ensure education costs remain affordable and aligned with students' needs.
Rangga Firdaus +4 more
openaire +1 more source
Education: A More Powerful Weapon Than War?
, 2015 In this paper, I analyze the impact of education on civil war onset, utilizing variables measuring length of compulsory education and number of internal armed conflicts in a given country per year.
Thomas, Maja K.
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Educational Federalism and the Quality Effects of Tuition Fees [PDF]
This paper investigates how the abolishment of a ban on tuition fees affects the quality of higher education with centralized and decentralized decision making.
Kemnitz, Alexander
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Assessment of the knowledge, attitudes and perceived quality of education about antimicrobial use and resistance of medical students in Zambia, Southern Africa. [PDF]
JAC Antimicrob Resist, 2023 Nowbuth AA +3 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source