Results 131 to 140 of about 1,557,415 (262)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A multi-tier fog content orchestrator mechanism with quality of experience support. [PDF]

Comput Netw, 2020
Santos H, Alencar D, Meneguette R, Rosário D, Nobre J, Both C, Cerqueira E, Braun T.   +7 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Quality of experience-aware application deployment in fog computing environments using machine learning. [PDF]

PeerJ Comput Sci
Jenifer P, Angela Jennifa Sujana J.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences. [PDF]

SLAS Discov, 2020
Roth JS, Lee TD, Cheff DM, Gosztyla ML, Asawa RR, Danchik C, Michael S, Simeonov A, Klumpp-Thomas C, Wilson KM, Hall MD.   +10 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

National Patient Satisfaction Survey as a Predictor for Quality of Care and Quality Improvement - Experience and Practice. [PDF]

Patient Prefer Adherence
Cui J, Du J, Zhang N, Liang Z.
europepmc   +1 more source

A Quality of Experience assessment of haptic and augmented reality feedback modalities in a gait analysis system. [PDF]

PLoS One, 2020
Braga Rodrigues T, Ó Catháin C, O'Connor NE, Murray N.   +3 more
europepmc   +1 more source