Results 111 to 120 of about 4,266,897 (334)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Quality of health care in Primary Care: perspective of people with Diabetes Mellitus. [PDF]

open access: yesRev Bras Enferm, 2023
Palasson RR   +7 more
europepmc   +1 more source

Scope of Online Maternal Health Information in Kinyarwanda and Opportunities for Digital Health Developers [PDF]

open access: yesarXiv
Maternal health literacy is associated with greater odds of positive pregnancy outcomes. There is an increasing proliferation of websites dedicated to maternal health education, but the scope and quality of their content varies widely. In this study, we analyzed the main topics covered on maternal health websites that offer content in the low-resource ...
arxiv  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Searching for non-English literature may be unnecessary for German HTA Reports [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved]

open access: yesF1000Research
Background Health technology assessment (HTA) reports are based on comprehensive information retrieval. Current standards discourage the use of search restrictions, such as publication date and language.
Stefan Sauerland   +5 more
doaj  

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