Results 111 to 120 of about 3,523,990 (313)

Sleep quality predicts quality of life in chronic obstructive pulmonary disease

open access: yesInternational Journal of COPD, 2010
Steven M Scharf1*, Nimrod Maimon2*, Tzahit Simon-Tuval3, Barbara J Bernhard-Scharf4, Haim Reuveni2, Ariel Tarasiuk21Department of Pulmonary and Critical Care, University of Maryland, Baltimore, MD, USA; 2Faculty of Health Sciences, Ben-Gurion University,
Tzahit Simon-Tuval   +3 more
doaj  

Validation of the cancer-specific utility measure EORTC QLU-C10D using evidence from four lung cancer trials covering six country value sets

open access: yesScientific Reports
The Quality of Life (QoL) Utility measure, QLU-C10D, is derived of the European Organisation for Research and Treatment of Cancer (EORTC) QoL Questionnaire, QLQ-C30.
Simone Seyringer   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Impact of Endometriosis on Women’s Quality of Life and Sexual Life

open access: yesArchives of Health Science and Research
Objective: This study was carried out to determine the effect of endometriosis on women’s sexual life and quality of life. Methods: A comparative descriptive study was conducted with 194 women (97 women diagnosed with endometriosis and 97 healthy ...
Melike DİŞSİZ   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Envisioning the Future of Music Therapy

open access: yes, 2016
Boyer College of Music and DanceMusic TherapyOn April 10, 2015, an international symposium, representing the 7th conference of the Arts and Quality of Life Research Center of the Boyer College of Music and Dance/Center for the Arts was held at Temple ...

core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

EMOTIONAL DESIGN AND QUALITY OF LIFE

open access: yes, 2017
Lately, the concept of emotional design, which implies the concept of improving the quality of life, happiness and satisfaction of a man, has greatly attracted the attention of the academic community.
Arsovski, Slavko   +4 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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