Results 71 to 80 of about 166,477,360 (253)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Consumer handbook for vocational rehabilitation services. 2013: Oct.

open access: yes, 2003
Title from PDF cover (viewed May 18, 2007).; "May 2003."; This handbook is designed to provide general information about the vocational rehabilitation program offered through the Connecticut Dept.
Connecticut. Bureau of Rehabilitation Services.
core  

A Survey on Medical Errors Reporting and Sharing Status In a Military Hospital -2012 [PDF]

open access: yesTaṣvīr-i salāmat, 2012
Background and objectives : Medical Errors reporting system is an initiative that provides staffs’ awareness through learning and sharing. This system improves the patient safety culture in hospitals.
Hamide Piri   +6 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Consumer handbook for vocational rehabilitation services. 2014: Apr.

open access: yes, 2003
Title from PDF cover (viewed May 18, 2007).; "May 2003."; This handbook is designed to provide general information about the vocational rehabilitation program offered through the Connecticut Dept.
Connecticut. Bureau of Rehabilitation Services.
core  

Other title: System and Services Acquisition Security Controls 2100-13

open access: yes, 2020
[2020 update]; At head of title: DAS Policy; "Effective date: 12/22/2017."; Policy number: 2100-13; "Revision history: 12/22/2017, Original Policy; 12/20/2018, Conducted review, no changes made to the policy as a result; 06/10/2020, Updated the policy ...
Ohio. Department of Administrative Services
core  

THE IMPACT OF A CHANGE IN THE POSITION OF THE REGIONAL TECHNICAL IMPLEMENTATION UNIT (UPTD) IN THE EDUCATION SECTOR TOWARDS THE QUALITY OF SECONDARY SCHOOL EDUCATION SERVICES IN EAST NUSA TENGGARA PROVINCE: A CASE STUDY ON GOVERNOR REGULATION NUMBER 32 OF 2019 REGARDING POSITION, ORGANIZATIONAL STRUCTURE, DUTIES, FUNCTIONS, AND WORK PROCEDURES OF THE OFFICE BRANCHES AND REGIONAL TECHNICAL IMPLEMENTATION UNITS OF EAST NUSA TENGGARA PROVINCE, INDONESIA

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
The purpose of this study was to describe and analyze the positive and negative impact of policy implementation that is changing the position of UPTD in the education sector towards the services it provides to teachers and education personnel in East ...
Hendi R.A., Petrus K., Nursalam
doaj   +1 more source

Alignment of software quality and service quality [PDF]

open access: yes, 1995
Software is today an integral or even main component of various service systems. Therefore it is of interest to analyze how software quality is related to service quality. Due to somewhat different nature of services and software, but also due to historical reasons, software quality models and service quality models differ a lot at first look.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Quality of Service and Service Provisioning on a Competitive Market [PDF]

open access: yes, 2000
The objective of this paper is to provide an economic and commercial context for QoS research in open distributed environments. The analyses are based on a telecommunications value chain model. The model is used to define possible roles for telecommunications companies, migrating from traditional telephony network operators towards privatised ICT ...
Lambert J. M. Nieuwenhuis, Ing Widya
openaire   +3 more sources

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