Results 51 to 60 of about 1,788,201 (258)

Surveying the Effect of Work-Life Balance on Quality of Life (Case Study : Hospitals of Sanandaj)

بیمارستان, 2015
Background: This study is aimed at investigating the effect of work-life balance in hospitals of Sanandaj. Work-life balance includes different aspects such as : family, work,leisure and personal growth.
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doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The effect of risk of contracting and fear of COVID-19 on burnout and job satisfaction in Polish teachers

Current Issues in Personality Psychology
Background Fear of COVID-19 and its related complications can negatively affect well-being and contribute to less effective daily and professional functioning.
Joanna Dymecka, Rafał Gerymski, Radoslaw B. Walczak, Aleksandra Jania   +3 more
doaj   +1 more source

PENGARUH QUALITY OF WORK LIFE TERHADAP MOTIVASI KERJA DAN KEPUASAN KERJA KARYAWAN

Matrik, 2016
This study aims to determine the effect on the Quality of Work Life Work Motivation and Job Satisfaction. The study was conducted at the Swastika Bungalows Sanur, with a sample of 60 employees who were taken with saturated or census sampling method. Data
Ni Luh Putu Surya Astitiani, Ida Bagus Ketut Surya   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Adaptation of the Work-Related Quality of Life-2 Scale (WRQoL-2) among Portuguese Workers

Societies
In the present study we aimed to fulfill two main goals. The first was to adapt the WRQoL-2 Scale among Portuguese workers and the second was to verify the associations between WRQoL-2 dimensions and perceived organizational performance dimensions (e.g.,
Ana Sabino, Ana Moreira, Francisco Cesário, Mafalda Pinto-Coelho   +3 more
doaj   +1 more source

The Health-Related Quality of Life, Work Productivity, Healthcare Resource Utilization, and Economic Burden Associated with Levels of Suicidal Ideation Among Patients Self-Reporting Moderately Severe or Severe Major Depressive Disorder in a National Survey

Neuropsychiatric Disease and Treatment, 2021
Carmela Benson,1 David Singer,2 Colleen M Carpinella,3 May Shawi,4 Larry Alphs4 1Real-World Value & Evidence, Janssen Scientific Affairs, LLC, Titusville, NJ, USA; 2Jefferson College of Population Health, Thomas Jefferson University, Philadelphia, PA,
Benson C, Singer D, Carpinella CM, Shawi M, Alphs L   +4 more
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source