Results 121 to 130 of about 9,296,950 (308)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
BMC Primary CareBackground Chronic diseases are heavily influenced by social determinants of health (SDoH), requiring care that extends beyond medical interventions to address underlying issues.
Rosanne Freak-Poli +6 more
doaj +1 more source
Programming Content and Quality
Law and Contemporary Problems, 1957 To its creator, a television or radio program may seem a work of art. To a station, or a network, it is a commodity to be sold, existing not so much for its own value, but so that the time it occupies may be sold and adjacent blocs of time may rise in market value.
openaire +2 more sources
Quality Improvement Division Annual Report 2016
, 2017 This report provides a high level overview of work completed by the Quality Improvement Division (QID) in 2016. In 2016 QID focused on developing and articulating the Framework for Improving quality that linked together the areas of work in Quality ...
Quality Improvement Division
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
PhysiologiaBackground: Childhood cancer survivors commonly experience long-term treatment effects that impair physical function. Access to in-person physical fitness assessments is often limited by geographic, logistical, and resource constraints.
Aidan O’Malley +9 more
doaj +1 more source
Program quality with pair programming in CS1
, 2005 In several regression applications, a different structural relationship might be anticipated for the higher or lower responses than the average responses. In such cases, quantile regression analysis can uncover important features that would likely be overlooked by mean regression. We develop two distinct Bayesian approaches to fully nonparametric model-
openaire +1 more source
Quality Improvement Division Operational Plan 2017
, 2017 The Quality Improvement Division provides advice and support quality improvement projects and initiatives. We do this by partnering with frontline services however the implementation of these programmes remains with the leadership of frontline ...
Quality Improvement Division
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
National Quality Improvement Team Annual Report 2017
, 2018 This report is a high level overview of work completed by the National Quality Improvement Team (formerly known as the Quality Improvement Division) in 2018.
National Quality Improvement Team
core