Results 131 to 140 of about 9,296,950 (308)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Roles of Administrators in Ensuring the Quality of Online Programs

open access: yesKnowledge Management & E-Learning: An International Journal, 2010
Roles of administrators are often overlooked when discussing the quality of online education. Administrators have long assumed the pivotal influence on school policies, faculty morale, and learning atmosphere.
Yi Yang
doaj  

Blockchain-Based Quality Assurance System for Academic Programs

open access: yesApplied Sciences
Nowadays, technology is increasingly being adopted in different kinds of businesses to process, store, and share sensitive information in digital environments that include enormous numbers of users.
Mohammad Alkhatib   +2 more
doaj   +1 more source

Quality and Patient Safety Division Annual Report 2014

open access: yes, 2015
A work plan is developed on an annual basis to support the quality and patient safety objectives in the National Service Plan. This report reviews the work completed in 2014 in delivery of the 2013 plan.
Quality Improvement Division
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Nutrition-Focused Quality Improvement Programs in Pediatric Care

open access: yesChildren
Nutrition is fundamental to a child’s growth and development. However, nutritional health is often compromised by acute and chronic conditions and treatments that can commonly result in malnutrition.
Amy R. Sharn   +5 more
doaj   +1 more source

Does the Quality of Training Programs Matter? Evidence from Bidding Processes Data [PDF]

open access: yes
This paper estimates the effect of training quality on labor-market earnings using a Peruvian non-experimental training program, PROJOVEN, which targets disadvantaged youths aged 16 to 24 years. The identification of causal effects is possible because of
José Galdo, Alberto Chong
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Do baseline requirements hinder trades in water quality trading programs? [PDF]

open access: yes
The Environmental Protection Agency and the U.S. Department of Agriculture are promoting point/nonpoint trading as a way of reducing the costs of meeting water quality goals while giving nonpoint sources a larger role in meeting those goals.
Ribaudo, Marc   +2 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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