Results 151 to 160 of about 2,852,414 (315)

Consumer responses to risk-benefit information about food

open access: yes, 2010
Communication about the healthiness of consuming different food products has typically involved either health messages about the associated risks or benefits.
van Dijk, H., Dijk, H., van
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Quality and Risk Management

open access: yes
The document titled "Accelerating Innovation and Entrepreneurial Excellence in Higher Education Institutes" outlines the development and implementation of a Quality and Risk Management System (QRMS) for a project supported by the European Institute of Innovation and Technology (EIT).
Van Looy, Bart   +2 more
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Leveraging Digital Twins for Quality Risk Management in Medium-Rise Residential Constructions

open access: yes
Traditional construction risk management approaches used by contractors to ensure the delivery of high-quality projects have been questioned. These approaches have been found to be inadequate, inefficient, and siloed.
Ullah, Fahim, Noah, Luper Joseph
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

TCEQ Regulatory Guidance

open access: yes, 2015
Guide used by the Texas Commission on Environmental Quality to develop "health- and welfare-based inhalation toxicity values, and health-based oral toxicity values." It also details the methods used to develop toxicity values and risk ...
Texas Commission on Environmental Quality. Toxicology Division.
core  

Quality by Design (QbD) and Quality Risk Management

open access: yes
Quality by Design (QbD) and Quality Risk Management (QRM) are modern scientific approaches that ensure pharmaceutical products are consistently safe, effective, and of high quality. Unlike traditional quality control methods that rely mainly on end-product testing, QbD emphasizes building quality into the product during development by understanding ...
Achyut Holagi   +2 more
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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