Results 171 to 180 of about 2,852,414 (315)

Quality of evidence must guide risk assessment of asbestos

, 2012
In 2011, we reported on the sensitivity of lung cancer potency estimates for asbestos to the quality of the exposure assessment component of underlying evidence.
Heederik, D., Stayner, L., Lenters, V.C., Vermeulen, R., Burdorf, A.   +4 more
core  

Statistical modeling for quality risk assessment of clinical trials: follow-up at the era of remote auditing

, 2021
Koneswarakantha B, Ménard T.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Research on PIVAS risk assessment and control strategy based on quality risk management (QRM). [PDF]

Explor Res Clin Soc Pharm
Qiu Q, Zhu G, Peng G, Chen Z, Zhu Z, Zhou Y, Ye Y, Shen Y, Wang L.   +8 more
europepmc   +1 more source

Swimming pools quality risk assessment for heavy metal deposition and intake via oral and dermal exposure. [PDF]

Environ Anal Health Toxicol, 2019
Nnabugwu AE, Uchenna AP.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Managing risk in the non self-accrediting higher education provider (NSA-HEP) sector

, 2011
There are two intertwined themes in this paper. The first theme, the management of risk in NSA-HEPs, is grounded in the AUQA reports to March 2011. The second theme reflects the policy settings that frame an approach to risk management.
Winchester, Hilary P. M., Brett, Kevin J.   +1 more
core  

Quality risk management for microbial control in membrane-based water for injection production using fuzzy-failure mode and effects analysis. [PDF]

PeerJ Comput Sci
Zhu L, Liang Y.
europepmc   +1 more source

Dietary Patterns and Poor Semen Quality Risk in Men: A Cross-Sectional Study. [PDF]

Nutrients, 2018
Danielewicz A, Przybyłowicz KE, Przybyłowicz M.   +2 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source