Results 141 to 150 of about 12,856,576 (256)

PRODUCT QUALITY AND DISTRIBUTION CHANNELS [PDF]

We introduce strategic behaviour in assigning a certain distribution channel to a product of a particular quality. We propose a variety of models to analyze and study some of the determinants of the choice of distribution channels.
José J. Sempere Monerris, Amparo Urbano, Rafael Moner Colonques   +2 more
core  

Essential Oil Quality in Medicinal and Aromatic Plants: Linking Plant Biosynthesis, Matrix Selection and Extraction Strategy. [PDF]

Plants (Basel)
Youchret-Zallez OB, Spigarelli R, Kouki A, Mbirki L, Ben-Attia M, Bernacchi A, Valerii MC, Spisni E.   +7 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Introducing the Quality Target Administration (QTAP) Profile for Enteral Feeding Tube Medications. [PDF]

Pharmaceutics
Salunke S, Chan CKA, Hu S.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Mixed oligopoly, vertical product differentiation and fixed quality-dependent costs [PDF]

A private and a public firm face fixed quality-dependent costs of production and compete first in quality and then either in prices or in quantities. In the long run the public firm targets welfare maximization whereas the private firm maximizes profits.
Mario Pezzino, Stefan Lutz
core  

Expanding Quantitative Medicines' Reach: Systems and Methods to Enhance R&D Productivity and Decision-Making in the Agentic-Era. [PDF]

Clin Transl Sci
Corrigan BW, Anderson E, Tredennick A, Martinez Lomeli L, Pane MC, Dunlap T, Davis B, Rogers J, Gastonguay MR.   +8 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Does tougher import competition foster product quality upgrading ? [PDF]

Over the past two decades, globalization, and more specifically the increased exposure to competition from low-price producers in China and India, has created a new economic environment for other emerging economies.
Fernandes, Ana M., Paunov, Caroline
core  

Anticancer Peptides: Design Principles, Translational Bottlenecks, and Emerging Opportunities. [PDF]

Molecules
Di ME, Di YP.
europepmc   +1 more source