Results 1 to 10 of about 46,629 (164)

Quality by Design Guided Development of Polymeric Nanospheres of Terbinafine Hydrochloride for Topical Treatment of Onychomycosis Using a Nano-Gel Formulation

Pharmaceutics, 2022
Superficial fungal diseases of the skin and nails are an increasingly common occurrence globally, requiring effective topical treatment to avoid systemic adverse effects.
Vinam Puri, Anna Froelich, Parinbhai Shah, Shernelle Pringle, Kevin Chen, Bozena Michniak-Kohn   +5 more
doaj   +3 more sources

Low-Affinity NMDA Receptor Antagonist Hemantane in a Topical Formulation Attenuates Arthritis Induced by Freund’s Complete Adjuvant in Rats [PDF]

Advanced Pharmaceutical Bulletin
Purpose: N-methyl-D-aspartate (NMDA) receptors that are expressed by T-cells modulate T-cell proliferation, cytotoxicity and cell migration toward chemokines. Several studies have shown an anti-inflammatory effect of NMDA receptor antagonists. This study
Elena Ivanova, Alexander Matyushkin, Alexandra Sorokina, Svetlana Alexeeva, Irina Miroshkina, Kirill Kachalov, Tatyana Voronina, Andrey Durnev   +7 more
doaj   +2 more sources

Comparative study of liposomes and liposomes-in-polymer hydrogel as transdermal carriers for improving the topical delivery of imperatorin

Journal of Holistic Integrative Pharmacy, 2021
[Abstract]: Objective: A novel imperatorin (IMP)-liposome-hydrogel formulation was developed to increase skin permeation efficiency and improve the bioavailability of IMP after topical delivery.
Junfeng BAN, Zhenjie MO, Xuehui CUI, Yuan XU, Zhufen LYU   +4 more
doaj   +1 more source

Polyaphron Dispersion Technology, A Novel Topical Formulation and Delivery System Combining Drug Penetration, Local Tolerability and Convenience of Application [PDF]

Dermatology and Therapy, 2022
Morten Praestegaard
exaly   +2 more sources

An insight into the use and advantages of Carbopol in topical mucoadhesive drug delivery system: A systematic review

Journal of Pharmacy, 2023
Introduction: In recent years, mucoadhesive topical application of mucous membrane has gained considerable interest among formulation researchers in advanced drug delivery systems.
Nurul Ain Mohammad Hamdi, Nurul Atifah Azmi, Nurul Hanis Mohd Sabari, Ahmad Fahmi Harun, Muhammad Salahuddin Haris   +4 more
doaj   +1 more source

Design, Formulation, and Evaluation of Aloe vera Gel-Based Capsaicin Transemulgel for Osteoarthritis

Pharmaceutics, 2022
Topical treatments are a potential therapeutic option for the therapy of osteoarthritis, with significant data supporting the effectiveness and safety of topical formulation.
Narayana Charyulu Rompicherla, Punam Joshi, Amitha Shetty, Kalvatala Sudhakar, Hawraz Ibrahim M. Amin, Yachana Mishra, Vijay Mishra, Aqel Albutti, Naif Alhumeed   +8 more
doaj   +1 more source

Design, Formulation and Evaluation of Diclofenac Diethylamine Gel

Journal of Basic and Applied Research in Biomedicine, 2022
The goal of this study was to produce a topical gel formulation of Diclofenac diethylamine using various gelling agents, such as carbopol 934, Sodium Carboxy methyl cellulose, and alovera extract, to reduce the gastrointestinal side effects associated ...
Sudipta Das, Keya Sarkar, Baishali Ghosh, Chandrima Saha   +3 more
doaj   +1 more source

Topical NSAID Formulations [PDF]

Pain Medicine, 2013
This article reviews topical nonsteroidal anti-inflammatory drug (NSAID) formulations available in the United States, including advantages and disadvantages, therapeutic usefulness, adverse effects, and formulation considerations.In the United States, several topical NSAID products are approved to treat painful conditions including diclofenac sodium 1%
Mary Lynn, McPherson, Nina M, Cimino
openaire   +2 more sources

Urea‐containing topical formulations [PDF]

International Journal of Clinical Practice, 2020
Urea is a well-known moisturiser and keratolytic topical agent. As it is widely used in dermatology, several formulations at different concentrations have been marketed: lotions, creams, foams, ointments, gels and lacquers. Availability of different vehicles and concentration may vary in different countries, but in general products at low, medium and ...
Annunziata M. C., Cacciapuoti S., Cosentino C., Fabbrocini G.   +3 more
openaire   +4 more sources

Synthesis of enhanced lipid solubility of indomethacin derivatives for topical formulations

Heterocyclic Communications, 2022
Indomethacin is a nonselective nonsteroidal anti-inflammatory drug with serious side effects such as depression, hallucination, and gastrointestinal irritation. This study aims to enhance indomethacin lipid solubility of indomethacin derivative to use it
Abualhasan Murad, Jaradat Nidal, Maslamani Raghad, Nofal Dana, Omar Linda   +4 more
doaj   +1 more source