Results 221 to 230 of about 12,856,576 (256)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Microfluidic-based rapid generation of chimeric antigen receptor T cells improves low-multiplicity-of-infection transduction efficiency while preserving functional activity. [PDF]

J Transl Med
Jiang Y, Zhu G, Zhang H, Tang D.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Beyond Precision: A Multidimensional Framework for Selecting Genetic Medicine Platforms. [PDF]

Cells
Wieland J, Jackson P, Penrod W, Nadauld S, Barrott J.   +4 more
europepmc   +1 more source

Dietary Antioxidants and Nrf2-Related Redox Responses in Sheep: Evidence, Limitations, and Implications for Health and Productivity. [PDF]

Vet Sci
Rehman SU, Shaukat A, Tharwat M, Khan AY, Alkheraif AA, Ali R.   +5 more
europepmc   +1 more source

Original rDNA Semaglutide Versus Synthetic Copies: Differences and Clinical Implications. [PDF]

Cureus
Mohan V, Kalra S, Ahluwalia A, Gangopadhyay KK, Bhattacharyya A, Saboo B, Kesavadev J, Ramakrishnan S, Lakhani OJ, Nagendra L, Sahoo AK, Joshi A, V Sri N, Joshi SR.   +13 more
europepmc   +1 more source

Therapeutic Monoclonal Antibodies as Advanced Therapies for Companion Animals: Species Adaptation, Fc Biology, Clinical Translation, and Future Platforms. [PDF]

Vet Sci
Fu Y, Guo Z, Wang H.
europepmc   +1 more source

Optimization of gemifloxacin immediate-release tablets using quality by design. [PDF]

J Food Drug Anal
Kim JW, Kang JS, Kim YH, Kim KM.
europepmc   +1 more source