Results 21 to 30 of about 9,681 (286)

Quantal Ca2+ release mediated by very few IP3 receptors that rapidly inactivate allows graded responses to IP3

open access: yesCell Reports, 2021
Summary: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels that link extracellular stimuli to Ca2+ signals. Ca2+ release from intracellular stores is “quantal”: low IP3 concentrations rapidly release a fraction of the stores.
Ana M. Rossi   +5 more
doaj   +1 more source

A Game Theoretical Model for Anticipating Email Spear-Phishing Strategies [PDF]

open access: yesEAI Endorsed Transactions on Scalable Information Systems, 2021
A solution to help victims against phishing is anticipating and leveraging impacts related to phisher actions.In this regard, this work reshapes game theoretical logic between Intrusion Detection System (IDS) agents andinsiders to email spear-phishing ...
Franklin Tchakounte   +4 more
doaj   +1 more source

Vestibular Testing—New Physiological Results for the Optimization of Clinical VEMP Stimuli

open access: yesAudiology Research, 2023
Both auditory and vestibular primary afferent neurons can be activated by sound and vibration. This review relates the differences between them to the different receptor/synaptic mechanisms of the two systems, as shown by indicators of peripheral ...
Christopher J. Pastras, Ian S. Curthoys
doaj   +1 more source

Quantal Responses to Mixtures of Poisons

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1952
Summary Various models for the joint action of poisons are examined. An attempt is made to clarify the differences between similar and dissimilar physiological actions; in similar action, the poisons act at a common site, whereas in dissimilar action each acts at a different site.
Plackett, R. L., Hewlett, P. S.
openaire   +2 more sources

Relevance and evaluation of the benchmark dose in toxicology [PDF]

open access: yesArhiv za farmaciju, 2020
This paper aims to present the importance of the benchmark dose (BMD) as a point of departure (the lowest dose or concentration in the experiment that deviates from the response that differs from the normal response) in toxicological risk assessment, as ...
Baralić Katarina   +7 more
doaj   +1 more source

Presynaptic molecular determinants of quantal size

open access: yesFrontiers in Synaptic Neuroscience, 2016
The quantal hypothesis for the release of neurotransmitters at the chemical synapse has gained wide acceptance since it was first worked out at the motor endplate in frog skeletal muscle in the 1950s.
Shigeo eTakamori
doaj   +1 more source

Optical Quantal Analysis

open access: yesFrontiers in Synaptic Neuroscience, 2019
Understanding the mechanisms by which long-term synaptic plasticity is expressed remains an important objective in neuroscience. From a physiological perspective, the strength of a synapse can be considered a consequence of several parameters including ...
Matthew J. MacDougall, Alan Fine
doaj   +1 more source

Estimation of cumulative amplitude distributions of miniature postsynaptic currents allows characterising their multimodality, quantal size and variability

open access: yesScientific Reports, 2023
A miniature postsynaptic current (mPSC) is a small, rare, and highly variable spontaneous synaptic event that is generally caused by the spontaneous release of single vesicles.
Susanna Gordleeva   +3 more
doaj   +1 more source

How Moral Codes Evolve in a Trust Game

open access: yesGames, 2015
This paper analyzes the dynamic stability of moral codes in a two population trust game. Guided by a moral code, members of one population, the Trustors, are willing to punish members of the other population, the Trustees, who defect.
Jean Paul Rabanal, Daniel Friedman
doaj   +1 more source

Benchmark dose approach in investigating the relationship between blood metal levels and reproductive hormones: Data set from human study

open access: yesEnvironment International, 2022
The main objective of this research was to conduct a dose–response modeling between the internal dose of measured blood Cd, As, Hg, Ni, and Cr and hormonal response of serum testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH ...
Katarina Baralić   +9 more
doaj   +1 more source

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