Results 51 to 60 of about 928,612 (281)

Reproductive success through high pollinator visitation rates despite self incompatibility in an endangered wallflower [PDF]

, 2016
PREMISE OF THE STUDY: Self incompatibility (SI) in rare plants presents a unique challenge—SI protects plants from inbreeding depression, but requires a sufficient number of mates and xenogamous pollination. Does SI persist in an endangered polyploid? Is
Herman, Julie A., Lucas, Jessica, Melen, Miranda K., O’Malley, Rachel E., Parker, Ingrid M., Thom, Aaron M., Whittall, Justen B.   +6 more
core   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Narratives in numbers: Sociotechnical storytelling with self-tracking

Memory, Mind & Media
This paper explores self-tracking as a social practice with significant relationships to human memory. The history of data and memory is fraught with a concern that specifics of qualia are subjugated to datafication.
Ben Lyall
doaj   +1 more source

New Frontiers of Quantified Self: Finding New Ways for Engaging Users in Collecting and Using Personal Data [PDF]

, 2015
In spite of the fast growth in the market of devices and applications that allow people to collect personal information, Quantified Self (QS) tools still present a variety of issues when they are used in everyday lives of common people.
Cena, Federica, Hopfgartner, Frank, Kay, Judy, Kummerfeld, Bob, Larsen, Jakob Eg, Plumbaum, Till, Rapp, Amon   +6 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Die digitale Selbstvermessung in Lifestyle und Medizin : eine Studie zur Technikfolgenabschätzung [PDF]

, 2018
Digital self-quantification, also known as quantified self (QS), refers to the measuring and recording of body parameters and conditions using apps and wearables.
Becker, Heidrun Karin, Evers-Wölk, Michaela, Hegyi, Stefan, Meidert, Ursula, Prieur, Yvonne, Scheermesser, Mandy   +5 more
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Self-organization and symmetry-breaking in two-dimensional plasma turbulence [PDF]

, 2010
The spontaneous self-organization of two-dimensional magnetized plasma is investigated within the framework of magnetohydrodynamics with a particular emphasis on the symmetry-breaking induced by the shape of the confining boundaries.
Bos, Wouter, Neffaa, Salah, Schneider, Kai   +2 more
core   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Quantified Self Analytics Tools for Self-regulated Learning with myPAL [PDF]

, 2017
One of the major challenges in higher education is developing self-regulation skills for lifelong learning. We address this challenge within the myPAL project, in medical education context, utilising the vast amount of student assessment and feedback ...
Dimitrova, V, Harkin, P, Kirby, J, Piotrkowicz, A, Roberts, T, Smithies, A, Treasure-Jones, T   +6 more
core