Results 111 to 120 of about 354,417 (335)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

From Play to Understanding: Large Language Models in Logic and Spatial Reasoning Coloring Activities for Children

AI
Visual thinking leverages spatial mechanisms in animals for navigation and reasoning. Therefore, given the challenge of abstract mathematics and logic, spatial reasoning-based teaching strategies can be highly effective.
Sebastián Tapia-Mandiola, Roberto Araya
doaj   +1 more source

On Spatial Conjunction as Second-Order Logic

, 2004
Spatial conjunction is a powerful construct for reasoning about dynamically allocated data structures, as well as concurrent, distributed and mobile computation.
Kuncak, Viktor, Rinard, Martin
core   +3 more sources

Quantification of Neutral Cysteine Protease Bleomycin Hydrolase and its Localization in Rat Tissues [PDF]

, 2007
Y. Kamata, Y. Itoh, A. Kajiya, S. Karasawa, C. Sakatani, S. Takekoshi, R. Y. Osamura, A. Takeda   +7 more
openalex   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Quantifying the spatial associations of terrain parameters from digital elevation models

, 2023
Zhong Yutao, Guoan, Tang
openalex   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Les adjectifs primaires: entre quantité et qualité [PDF]

Studii de Lingvistica, 2011
This paper aims at describing how qualification and quantification meet when quantity nouns are accompanied by a quantifier and a basic adjective. As in English, the combination between a quantifier and a basic adjective can be interpreted as a complex ...
Jan Goes
doaj