Results 111 to 120 of about 11,547 (304)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Notre Dame Journal of Formal Logic, 1987 This paper is a logical defense of the essential rightness of the Scholastic theory of distribution, the theory of distributed and undistributed terms. This theory has been severely attacked by Peter Geach, who regards it as a blot on the history of logic. I, in fact, agree with Geach's criticisms themselves, but I wish to overturn his ultimate verdict.
openaire +3 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
On the positions of floated quantifiers [PDF]
, 2005 The stranding analysis of floated quantifiers (Sportiche 1988) predicts that quantifiers can be stranded in their base-generated positions. This is not, however, always the case (e.g., *The students were arrested all).
Ôno, Masaki
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Mid-scalar quantifiers in Latin [PDF]
, 2010 We define as ‘mid-scalar’ those quantifiers which express a quantity and which, on a scale from a minimal to a maximal quantity, appear near the middle.
BERTOCCHI, ALESSANDRA, MARALDI, MIRKA
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
, 2000 The main goal of the thesis is to present a novel analysis of comparative quantifiers such as more than three students. The prevalent view on such expressions advocated in Generalized Quantifier Theory is that they denoted generalized quantifiers ranging
Martin Hackl, Irene Heim
core
AIVisual thinking leverages spatial mechanisms in animals for navigation and reasoning. Therefore, given the challenge of abstract mathematics and logic, spatial reasoning-based teaching strategies can be highly effective.
Sebastián Tapia-Mandiola, Roberto Araya
doaj +1 more source