Results 121 to 130 of about 354,417 (335)
Quantify the energy and environmental benefits of implementing energy-efficiency measures in China’s iron and steel production [PDF]
, 2015 Ding Ma, Wenying Chen, Tengfang Xu
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Acquisition of L2 English Negative Quantifiers without Equivalent Lexical Items in an L1
Theory and Practice of Second Language AcquisitionThis article investigates how second language learners interpret a scope bearing item in the target language. According to Sprouse (2006), L2 learners’ task is to relabel their native language’s lexical items in line with the features of the target ...
Masaaki Kamiya, Zhaosen Guo
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
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Frozen accusative forms in Croatian
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2008 In this paper the author analyzes nouns which are used to determine measure (such as stotinu, tisuću, godinu, tjedan…). They usually come in a frozen form, formally accusative, although syntactic rules require another form.
Ivana Matas Ivanković
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
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Quantifying Structural Deficit in the Lower Colorado River Basin
, 2020 Madeline Tennant, Amy Carmellini
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