Results 121 to 130 of about 11,536 (304)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Quantifiers and Partiality

open access: yes, 1995
This paper investigates the behaviour of binary quantifiers in settings of incomplete information, i.e., in partial models. The framework to handle informational partiality that is presented in this paper is relevant for the behaviour of quantifiers in ...
Jan van Eijck
core  

Understanding quantifiers in language [PDF]

open access: yes, 2009
We compare time needed for understanding different types of quantifiers. We show that the computational distinction between quantifiers recognized by finite-automata and push-down automata is psychologically relevant.
Szymanik, J., Zajenkowski, M.
core   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Frozen accusative forms in Croatian

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2008
In this paper the author analyzes nouns which are used to determine measure (such as stotinu, tisuću, godinu, tjedan…). They usually come in a frozen form, formally accusative, although syntactic rules require another form.
Ivana Matas Ivanković
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Connectionist modeling of linguistic quantifiers

open access: yes, 2005
This paper presents a new connectionist model of the grounding of linguistic quantifiers in perception that takes into consideration the contextual factors affecting the use of vague quantifiers. A preliminary validation of the model is presented through
Cangelosi, A.; id_orcid   +4 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Comparative quantifiers [PDF]

open access: yes, 2001
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, February 2001.Includes bibliographical references (leaves 187-193).The main goal of the thesis is to present a novel analysis of comparative quantifiers such as ...
Hackl, Martin, 1968-
core  

Quantifiers in Russian Sign Language

open access: yes, 2017
After presenting some basic genetic, historical and typological information about Russian Sign Language, this chapter outlines the quantification patterns it expresses. It illustrates various semantic types of quantifiers, such as generalized existential,
Kimmelman, V., Vadim Kimmelman
core   +1 more source

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