Results 271 to 280 of about 383,746 (345)

TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway. [PDF]

Cell Commun Signal
Li J, Li J, Xie T, Huang S, Tian H, Liu M, Kong X, Zhang D, Nawaz KI, Wang M, Li H, Zhang J, Yuan F, Guo W, Cui X, Mu H, Hu Y.   +16 more
europepmc   +1 more source

Absolute Quantification of Brain Deuterium Metabolic Imaging in Healthy Volunteers and Glioblastoma Patients at 7T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose We present a method for absolute quantification of deuterated metabolites in vivo at 7T. We describe acquisition protocols and an analysis pipeline compatible with 7T Terra MRIs. We apply them using a 2H/1H receive array in healthy volunteers and glioblastoma patients.
Jabrane Karkouri, Masha Novoselova, Sarah Miller, Minghao Zhang, Alexandra Constantinou, Carina Graf, Özlem Ipek, Daniel Atkinson, Brandon Tramm, Scott Schillak, Richard Mair, Kevin Brindle, Christopher T. Rodgers   +12 more
wiley   +1 more source

VOC Emission Screening of Consumer Products in Microchambers: Comparison of Online PTR-MS and Offline TD-GC-MS Analysis. [PDF]

Anal Chem
Klein L, Haug H, Stenzel A, Beauchamp J, Roloff A.   +4 more
europepmc   +1 more source

Development of a Sustainable Biocatalytic Process for Geranyl Benzoate Production Using Immobilized Lipase

ChemistryOpen, EarlyView.
This study optimized solvent‐free geranyl benzoate production using Lipozyme 435, achieving 72% conversion in 6 hours. Open reactors improved yields (>99% in 48 hours) by removing inhibitorymethanol. Methyl benzoate reduced enzyme activity by 54%, though Lipura Flex showed better resistance. Human cell tests confirmed no cytotoxicity.
Domenico Meola, Chaimae Chaibi, Simona Aprile, Karina Cesca, Debora de Oliveira, Ariela Veloso de Paula, Francesco Presini, Federico Zappaterra, Pier Paolo Giovannini, Lindomar Alberto Lerin   +9 more
wiley   +1 more source

Exosomes displaying native EGF enhance doxorubicin's therapeutic efficacy and reduce cardiotoxicity. [PDF]

J Nanobiotechnology
Mao L, Qian L, Zhou X, Niu K, Li Z, Wang S, Xie J, Zhou W, Dang X.   +8 more
europepmc   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

pH-Activatable engineered nanoparticle-based selective hexokinase 2 degrader provokes GSDME-dependent pyroptosis for cancer therapy. [PDF]

Acta Pharm Sin B
Gong L, Li S, Sun J, Liu K, Wang S, Ji M, Hou P, Yan L, Yang D, Liu D.   +9 more
europepmc   +1 more source

ADAM17-dependent Autocrine and Paracrine Signaling Promotes Pancreatic Premalignant Progression. [PDF]

Cell Mol Gastroenterol Hepatol
Wen HJ, Davis ET, Moore JS, Brender SM, Benitz S, Wombwell AM, Loveless IM, Long DW, Salas-Escabillas DJ, Lee J, Devorkin BS, McQuithey H, Steele NG, Hurt E, Crawford HC.   +14 more
europepmc   +1 more source

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons. [PDF]

NAR Cancer
Vendetti FP, Pandya P, Sclafani CR, Pathak S, Buj R, Jones RE, Ivanov D, Aird KM, Sobol RW, Bakkenist CJ.   +9 more
europepmc   +1 more source