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Inhibition or genetic reduction of ASAH1/acid ceramidase restore α-synuclein clearance in mutant GBA1 dopamine neurons from Parkinson's patients. [PDF]

Hum Mol Genet
Kumar M, Feldman RA.
europepmc   +1 more source

PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling. [PDF]

Proc Natl Acad Sci U S A
Cen Y, R Alves S, Song D, Felice C, Preall JB, Van Aelst L, Tonks NK.   +6 more
europepmc   +1 more source

Microgliopathy as a primary mediator of neuronal death in models of Friedreich's Ataxia. [PDF]

Nat Commun
Pernaci C, Johnson A, Gillette S, Warden AS, McCormick C, Weiser-Novak S, Ramirez G, Broersma EH, Mishra P, Sivakumar A, Cherqui S, Coufal NG.   +11 more
europepmc   +1 more source

Wastewater-based protocols for SARS-CoV-2: insights into virus concentration, extraction, and quantitation methods from two years of public health surveillance

Dagmara S. Antkiewicz, Kayley H. Janssen, Adélaïde Roguet, Hannah E. Pilch, Rebecca B. Fahney, Paige A. Mullen, Griffin N. Knuth, Devin G. Everett, Evelyn M. Doolittle, Kaitlyn King, Charles A. Wood, Angellica Stanley, Jocelyn D.C. Hemming, Martin M. Shafer   +13 more
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Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction.

Angewandte Chemie, 2020
Immunotherapy has revolutionized cancer treatment, but its efficacy is severely hindered by the lack of effective predictors. Herein, we developed a homogeneous, low-volume, efficient, and sensitive exosomal PD-L1 (HOLMES-ExoPD-L1 ) quantitation method ...
Mengjiao Huang, Juanjuan Yang, Teng Wang, Jia Song, Jing Xia, Lingling Wu, Wei Wang, Qiaoyi Wu, Zhi Zhu, Yanling Song, C. Yang   +10 more
semanticscholar   +1 more source