Results 51 to 60 of about 789,997 (243)

Unveiling Public Innovation Management: What Data Mining Reveals by Analyzing Brazilian Experiences?

BAR: Brazilian Administration Review
Objective: the purpose of this article is to explain public sector innovation management, based on Brazilian experiences in public administration, relating six dimensions of innovation: drivers, facilitators, barriers, capabilities, outcomes, and impacts
Antonio Isidro da Silva Filho, Dayse Karenine de Oliveira Carneiro, Fernando de Souza Coelho   +2 more
doaj   +1 more source

Les réseaux d'enseignants – Quels sont les comportements rédactionnels des locuteurs ?

ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2012
Over the past decade, teachers have created and animated corporate networks based on technologies of the Web 2.0 outside the strict institutional hierarchy. Yet little studied, many of these online networks are now welcomed with great success. The aim of
Isabelle Quentin
doaj   +1 more source

An Efficient Rigorous Approach for Identifying Statistically Significant Frequent Itemsets [PDF]

, 2009
As advances in technology allow for the collection, storage, and analysis of vast amounts of data, the task of screening and assessing the significance of discovered patterns is becoming a major challenge in data mining applications.
Kirsch, Adam, Mitzenmacher, Michael, Pietracaprina, Andrea, Pucci, Geppino, Upfal, Eli, Vandin, Fabio   +5 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants

Blood Advances, 2019
: Standardized variant curation is essential for clinical care recommendations for patients with inherited disorders. Clinical Genome Resource (ClinGen) variant curation expert panels are developing disease-associated gene specifications using the 2015 ...
Xi Luo, Simone Feurstein, Shruthi Mohan, Christopher C. Porter, Sarah A. Jackson, Sioban Keel, Michael Chicka, Anna L. Brown, Chimene Kesserwan, Anupriya Agarwal, Minjie Luo, Zejuan Li, Justyne E. Ross, Panagiotis Baliakas, Daniel Pineda-Alvarez, Courtney D. DiNardo, Alison A. Bertuch, Nikita Mehta, Tom Vulliamy, Ying Wang, Kim E. Nichols, Luca Malcovati, Michael F. Walsh, Lesley H. Rawlings, Shannon K. McWeeney, Jean Soulier, Anna Raimbault, Mark J. Routbort, Liying Zhang, Gabriella Ryan, Nancy A. Speck, Sharon E. Plon, David Wu, Lucy A. Godley   +33 more
doaj   +1 more source

Mining Top-k High Average-Utility Sequential Patterns for Resource Transformation

Applied Sciences, 2023
High-utility sequential pattern mining (HUSPM) helps researchers find all subsequences that have high utility in a quantitative sequential database. The HUSPM approach appears to be well suited for resource transformation in DIKWP graphs.
Kai Cao, Yucong Duan
doaj   +1 more source

Mining Target-Oriented Fuzzy Correlation Rules to Optimize Telecom Service Management

, 2011
To optimize telecom service management, it is necessary that information about telecom services is highly related to the most popular telecom service. To this end, we propose an algorithm for mining target-oriented fuzzy correlation rules. In this paper,
Chueh, Hao-En
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

“An ethnographic seduction”: how qualitative research and Agent-based models can benefit each other [PDF]

, 2010
We provide a general analytical framework for empirically informed agent-based simulations. This methodology provides present-day agent-based models with a sound and proper insight as to the behavior of social agents — an insight that statistical data ...
Agar MH, Allan G., Aquino P., Axelrod R., Axtell R., Bankes SC, Burawoy M., Gilbert N., Gilbert N., Gilbert N., Glaser BG, Hassan S., Headland T., Kelle U, Phan D, Rouchier J., Schelling T., Small C., Wilensky U., Wilensky U., Yin R., Zeigler BP   +21 more
core   +4 more sources