Results 11 to 20 of about 54,719 (127)

Robot life: simulation and participation in the study of evolution and social behavior. [PDF]

, 2018
This paper explores the case of using robots to simulate evolution, in particular the case of Hamilton's Law. The uses of robots raises several questions that this paper seeks to address.
AE Eiben, ANH Creager, B Bensaude-Vincent, C Kelty, Christopher M. Kelty, D Floreano, D Floreano, D Goldberg, DA Levitis, DW Smith, E Winsberg, EF Keller, EG Leigh, F Steinle, FJ Varela, H Landecker, H Landecker, H Landecker, H Landecker, J Dupré, J Krause, J Lenhard, J Riskin, JA Kurland, JA Piliavin, JC Schank, L Berthouze, L Berthouze, L Suchman, LR Franklin, M Asada, M Lungarella, M Waibel, MA Nowak, P Humphreys, P Huneman, R Pfeifer, RM Bergner, RR Kline, S Dutreuil, S Garnier, S Helmreich, S Helmreich, S Mitri, S Mitri, S Mitri, S Okasha, S Schweber, SF Gilbert, Stephen J Gould, T Grune-Yanoff, W Parker, WC Wimsatt, WD Hamilton   +53 more
core   +1 more source

Connecting the Brain to Itself through an Emulation. [PDF]

, 2017
Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition.
Serruya, Mijail D.
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Brain Dynamics across levels of Organization [PDF]

, 2006
After presenting evidence that the electrical activity recorded from the brain surface can reflect metastable state transitions of neuronal configurations at the mesoscopic level, I will suggest that their patterns may correspond to the distinctive ...
Werner, M.D. Gerhard
core  

Laminar fMRI: applications for cognitive neuroscience [PDF]

, 2019
The cortex is a massively recurrent network, characterized by feedforward and feedback connections between brain areas as well as lateral connections within an area.
de Lange, Floris P., Formisano, Elia, Lawrence, Samuel J.D., Muckli, Lars   +3 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A framework for Thinking about Distributed Cognition [PDF]

, 2006
As is often the case when scientific or engineering fields emerge, new concepts are forged or old ones are adapted. When this happens, various arguments rage over what ultimately turns out to be conceptual misunderstandings.
Chicoisne, Guillaume, Poirier, Pierre
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Memory and information processing in neuromorphic systems

, 2015
A striking difference between brain-inspired neuromorphic processors and current von Neumann processors architectures is the way in which memory and processing is organized.
Indiveri, Giacomo, Liu, Shih-Chii
core   +1 more source