Results 91 to 100 of about 7,422,915 (294)

Book Review: Great help for novice GT researchers

open access: yesGrounded Theory Review: An International Journal, 2016
The authors’ main purpose of the book is to provide practical guidance for novice researchers using classic grounded theory (GT) while remaining as true as possible to Glaser’s and Strauss’ thoughts.
Tove Giske
doaj  

How do emigrants perceive changes in their L1: influence of sociolinguistic factors

open access: yesTaikomoji kalbotyra, 2017
The paper aims at providing insights into sociolinguistic factors which affect the understanding of the first-generation emigrants that their L1 is different (or not) from Lithuanian used in Lithuania. The data for the analysis comes from the project The
Loreta Vilkienė
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Technique for experimental determination of radiation interchange factors in solar wavelengths [PDF]

open access: yes, 1971
Process obtains solar heating data which support analytical design. Process yields quantitative information on local solar exposure of models which are geometrically and reflectively similar to prototypes under study.
Bobco, R. P.   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

From the Editor

open access: yesGrounded Theory Review: An International Journal, 2007
This issue of the Review combines a strong focus on classic grounded theory methodology with our continued practice of featuring the work of novice grounded theorists.
Judith A. Holton
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Qualitative and Quantitative Research

open access: yesGrounded Theory Review: An International Journal, 2008
The main point in the next two chapters is that the methodological literature is filled with references to the quantitative-qualitative conflict or opposition.
Barney G. Glaser
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Automatic facial analysis for objective assessment of facial paralysis [PDF]

open access: yes, 2009
Facial Paralysis is a condition causing decreased movement on one side of the face. A quantitative, objective and reliable assessment system would be an invaluable tool for clinicians treating patients with this condition. This paper presents an approach
He, Shu   +3 more
core  

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