Results 91 to 100 of about 28,160,752 (309)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A Latent Variable Approach to Multivariate Quantitative Trait Loci [PDF]

open access: yes, 2010
A novel approach based on latent variable modelling is presented for the analysis of multivariate quantitative and qualitative trait loci. The approach is general in the sense that it enables the joint analysis of many kinds of quantitative and ...
Päivi Komulainen   +3 more
core  

Data for: Quantitative Analysis of Multimodal Speech Data

open access: yes, 2018
Data for "Quantitative Analysis of Multimodal Speech Data," including raw data, analysis scripts, and example optical flow videos. This data can be used to replicate the analyses in the manuscript according to the 'steps to reproduce ...
Gordon Danner, S (via Mendeley Data)
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Data from: Quantitative visual soil observation for visual soil evaluation on dairy farms

open access: yes, 2017
Quantitative visual observations were collected for two studies on dairy farms in the Netherlands. Data were collected following the same methodology (Van Leeuwen et al., 2018) based on Visual Soil Assessment of Shepherd (2009)
Quik, C. (Cindy)   +2 more
core   +1 more source

Book Review: Great help for novice GT researchers

open access: yesGrounded Theory Review: An International Journal, 2016
The authors’ main purpose of the book is to provide practical guidance for novice researchers using classic grounded theory (GT) while remaining as true as possible to Glaser’s and Strauss’ thoughts.
Tove Giske
doaj  

Art et topographie dans le Berlin réunifié

open access: yesCahiers d’Études Germaniques
This essay examines the working and living conditions of visual artists in Berlin since reunification, as well as the city’s significance in the German and global art scene.
Julio VELASCO
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Mississippi Semester: New Social Justice Approach to Teaching Empirical Reasoning in Context

open access: yesNumeracy, 2019
Under the direction of Professor Premilla Nadasen at Barnard College, the course “Mississippi Semester,” brings together a small group of undergraduate students in a collaborative action-driven project with Mississippi Low-Income Child-Care Initiative ...
Premilla Nadasen   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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