Transcription Factors as Important Regulators of Changes in Behavior through Domestication of Gray Rats: Quantitative Data from RNA Sequencing. [PDF]
Int J Mol Sci, 2022 Oshchepkov D +9 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Quantitative Data-Independent Acquisition Glycoproteomics of Sparkling Wine. [PDF]
Mol Cell Proteomics, 2021 Pegg CL +6 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Assessing School Engagement Intervention Dataset of Nigerian Pre-service TVET Teachers
Frontiers in Psychology, 2022 Godwin Keres Okoro Okereke +18 more
doaj +1 more source
Enhancing Interrogation of Skeletal Muscle Samples for Informative Quantitative Data. [PDF]
J Neuromuscul Dis, 2021 Partridge TA.
europepmc +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Theoretical Elaboration of Quantitative Data
Grounded Theory Review: An International Journal, 2007 Quantitative data is so closely associated with the current emphasis on verification that its possibilities for generating theory have been left vastly underdeveloped.
Barney G. Glaser
doaj
Relationship Between Teachers’ Feedback and Students’ Self-Efficacy Among Mathematics Majors
EDUCATIO: Journal of EducationThis study aims to investigate the relationship between teachers' feedback and students' self-efficacy among 33 Bachelor of Secondary Education students majoring in Mathematics at Holy Cross College, Rosa, N.E. Inc.
KC Ann B. Adelante +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source