Results 31 to 40 of about 602,860 (218)
Chemical Compositions, Chromatographic Fingerprints and Antioxidant Activities of Andrographis Herba
Molecules, 2014 This paper describes the development of an HPLC-UV-MS method for quantitative determination of andrographolide and dehydroandrographolide in Andrographis Herba and establishment of its chromatographic fingerprint.
Yang Zhao +5 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Investigation of the biological active compounds of crocus sativus stigmas (saffron) from Ukraine
Фармацевтичний журнал, 2019 Saffron, the most expensive spice in the world, comes from the Crocus sativus stigmas. Saffron grows well in the areas with the cold winters and warm dry summers, which have a positive effect on the quality of the raw material obtained. This explains the
O. O. Mykhailenko
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Spectrophotometric determination of sotalol in tablets
Фармацевтичний журнал, 2018 In this investigation a visible spectrophotometric method for the determination of sotalol based on the absorbance of colored product of the reaction between sotalol hydrochloride and bromcresol purple in acetone medium at 399 nm measurement was ...
Y. M. Zhuk, S. O. Vasyuk
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta PraktikiLeading pharmacopoeias of the world regulate performing chromatographic determination of enalapril in the substance using gradient elution (for 30 min) and a chromatographic column of 4.1 mm × 15 cm, 5 μm, class L21, at a temperature of 70 °C, with a ...
M. I. Druchok, L. S. Logoyda
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Quantitative determination of trifuzol in the 2.5% injection solution by spectrophotometric method
Фармацевтичний журнал, 2020 The effectiveness of the treatment of common diseases of the respiratory system, hematopoietic system, digestive system of livestock and domestic animals with the help of existing drugs is not always sufficient, and there is an urgent need to expand the ...
N. N. Borisenko +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. Caraway fruits are used in the treatment of irritable bowel syndrome and dyspeptic disorders due to their pronounced antispasmodic, antimicrobial, and carminative effects. The antispasmodic activity of caraway seeds isprimarily due to their
S. D. Ryumin +2 more
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