Results 81 to 90 of about 1,352,768 (318)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Abstracts, Review of Progress in Quantitative Nondestructive Evaluation (Green Bay, WI, July 27–August 1, 2003)

, 2003
s of papers presented at the 2003 Review of Progress in Quantitative Nondestructive Evaluation (QNDE) conference, held in Green Bay, Wisconsin from July 27–August 1, 2003.

core  

A quantitative theory of laser-generated ultrasound

, 2022
S.489-496The generation of broadband elastic waves in solids by laserpulses is a suitable tool for nondestructive evaluation. The basic equations for mathematical description of the generation mechanism follow directly from non-equilibrium thermodynamics
Arnold, W., Langenberg, K.-J., Schleichert, U., Fassbender, S.   +3 more
core  

Biomechanical mechanism and clinical management progress of surgical wound tension

Frontiers in Surgery
Surgical wound tension, a core biomechanical factor in tissue repair, is clinically important because high tension can cause microcirculatory disturbances, leading to inhibition of cell migration and collagen deposition, and increasing complications such
Feiyu Gong, Bingjie Wan, Ping Qi, Zairong Wei, Zairong Wei, Zairong Wei, Zairong Wei   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Abstracts, Review of Progress in Quantitative Nondestructive Evaluation (Baltimore, MD, July 21–26, 2013)

, 2013
s of papers presented at the 2013 Review of Progress in Quantitative Nondestructive Evaluation (QNDE) conference held in Baltimore, Maryland from July 21–26, 2013.

core  

Quantitative Evaluation of NDE Reliability

, 1989
A comprehensive reliability programme is being performed by the UKAEA and CEGB which is studying aspects such as inspection procedures, equipment, and data interpretation and reporting(1).
Gardner, W., W. E. Gardner, R. A. Murgatroyd, Murgatroyd, R.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Abstracts, Review of Progress in Quantitative Nondestructive Evaluation (Portland, OR, July 20–August 4, 2006)

, 2006
s of papers presented at the 2006 Review of Progress in Quantitative Nondestructive Evaluation (QNDE) conference held in Portland, Oregon from July 30–August 4, 2006.

core  

Depth Evaluation in Pulsed Phase Thermography with Neural Network

, 1999
Pulsed phase thermography (PPT) was recently introduced [1] and up to now analysis of this infrared thermographie approach for non destructive evaluation has been limited to qualitative aspects. The study presented in this paper uses a neural network (NN)
Maldague, X., X. Maldague, Y. Largouët, A. Darabi, Largouët, Y., Darabi, A.   +5 more
core   +1 more source