Results 111 to 120 of about 5,840,685 (292)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

QUANTITATIVE GENETICS [PDF]

open access: yesEvolution, 1999
Trudy F. C. Mackay   +2 more
openaire   +2 more sources

Resistance of Eucalyptus pellita to rust (Puccinia psidii) [PDF]

open access: yesCrop Breeding and Applied Biotechnology, 2014
Eucalypts rust (Puccinia psidii) is currently one of the major diseases in commercial eucalypt plantations in Brazil. The primary method of disease control is the use of resistant genotypes, and, among the different species of Eucalyptus, E. pellita is
Marisângela Rodrigues Santos   +5 more
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Quantitative Genetics and Evolution

open access: yesPeriodicum biologorum, 2010
Today, evolution is a unifying concept in biology. A century and half ago, Darwin developed the theory of natural selection, and proposed it as the mainmechanism of evolution. A quantitative approach to the study of evolution required new theoretical developments in population and quantitative genetics. Here, I review the basic concepts of quantitative
openaire   +2 more sources

Across borders – the status and future opportunities for long-term conservation of Nordic animal genetic resources

open access: yesGenetic Resources
The genetic diversity of multiple animal species is now declining rapidly, highlighting the need for action to protect and preserve animal genetic resources for the long term.
Ellen-Louisa F. White   +10 more
doaj   +1 more source

Platelet glycoprotein VI genetic quantitative and qualitative defects

open access: yesPlatelets, 2019
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for ...
Martine Jandrot-Perrus   +2 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

A new direction for farm animal genetic resources [PDF]

open access: yes, 2009
In September 2007, the International Technical Conference on Animal Genetic Resources for Food and Agriculture was held in Interlaken, Switzerland. Two important documents aiming at preventing the genetic erosion of farm animal biodiversity and promoting
Kantanen, Juha
core  

Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide Approach [PDF]

open access: yes, 2008
Background: The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for ...
Daetwyler, Hans D.   +14 more
core   +1 more source

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