Results 91 to 100 of about 5,840,685 (292)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
Cotsapas, Chris J., Liu, M.Y., Cowley, Mark J., Nott, David J., Little, Peter F., Peter F. R. Little, Chan, E.K.F., Cotsapas, C.J., Chan, Eva K., Luo, Oscar J., Cowley, M.J., Williams, Rohan B., Eva K. F. Chan, Pulvers, Jeremy N., Michael Y. Liu, Rohan B. H. Williams, Pulvers, J.N., David J. Nott, Williams, R.B.H., Little, P.F.R., Jeremy N. Pulvers, Oscar J. Luo, Mark J. Cowley, Luo, O.J., Chris J. Cotsapas, Nott, D.J., Liu, Michael Y.   +26 more
core   +1 more source

Assessment of genetic diversity in cowpea (Vigna unguiculata) [PDF]

Electronic Journal of Plant Breeding, 2010
Sixty six genotypes of cowpea (Vigna unguiculata (L.) Walp) were investigated to understand the extent of genetic diversitythrough twelve quantitative traits.
R.M.Nagalakshmi, R. Usha Kumari and M. B. Boranayaka
doaj  

Segmentation and classification of two-channel C. elegans nucleus-labeled fluorescence images

BMC Bioinformatics, 2017
Background Aging is characterized by a gradual breakdown of cellular structures. Nuclear abnormality is a hallmark of progeria in human. Analysis of age-dependent nuclear morphological changes in Caenorhabditis elegans is of great value to aging research,
Mengdi Zhao, Jie An, Haiwen Li, Jiazhi Zhang, Shang-Tong Li, Xue-Mei Li, Meng-Qiu Dong, Heng Mao, Louis Tao   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Genetic heterogeneity of residual variance in broiler chickens [PDF]

, 2006
Aims were to estimate the extent of genetic heterogeneity in environmental variance. Data comprised 99 535 records of 35-day body weights from broiler chickens reared in a controlled environment.
Rowe Suzanne J, Avendano, Santiago, Hill, William G., White, Ian M. S., White Ian MS, Ian M.S. White, Avendaño Santiago, Hill William G, Suzanne J. Rowe, William G. Hill, Suzanne J Rowe, Ian MS White, William G Hill, Santiago Avendaño, Rowe, Suzanne J.   +14 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

MULTIVARIATE ANALYSIS ON PHENOTYPIC TRAITS OF BODY MEASUREMENT IN SWAMP BUFFALO ( Bubalus bubalis)

Journal of the Indonesian Tropical Animal Agriculture, 2014
The objective of this research was to study the relationship between body measurement and bodyweight and closeness among swamp buffalo at three populations in Central Java.
S. Johari, E. Kurnianto, S. Sutopo, W.A. Hamayanti   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Environment-dependent genetic correlations between development time and body mass in a scorpionfly [PDF]

, 2007
Engqvist L. Environment-dependent genetic correlations between development time and body mass in a scorpionfly. Zoology. 2007;110(5):344-353.Development time and body mass at maturation are two important fitness traits fundamental for our understanding ...
Engqvist, Leif ; https://orcid.org/
core   +1 more source