Results 161 to 170 of about 5,840,685 (292)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Effect of population structure and stabilizing selection on quantitative genetic variation. [PDF]

Genetics
Li J, Hermisson J, Sachdeva H.
europepmc   +1 more source

Genetic Parameters of Growth Traits and Quantitative Genetic Metrics for Selection and Conservation of Mecheri Sheep of Tamil Nadu. [PDF]

Animals (Basel), 2023
Balasundaram B, Thiruvenkadan AK, Murali N, Muralidharan J, Cauveri D, Peters SO.   +5 more
europepmc   +1 more source

Q&A: Genetic analysis of quantitative traits

Journal of Biology, 2009
Mackay Trudy FC
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Quantitative Genetic Analysis of Baboon Facial Variation Challenges a Classic Papionin Trait. [PDF]

Integr Org Biol
Thiebaut A, Roseman CC, Mahaney MC, Hlusko LJ.   +3 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Assessment of Quantitative Genetic Distances Supports the Separation of H17N10 and H18N11 Subtypes of Influenza A Virus into a Distinct Species. [PDF]

Viruses
Volkhin IA, Dashian MA, Lukashev AN, Shipulin GA, Deviatkin AA.   +4 more
europepmc   +1 more source

Quantitative genetic analysis reveals potential to breed for improved white clover growth in symbiosis with nitrogen-fixing Rhizobium bacteria. [PDF]

Front Plant Sci, 2022
Weith SK, Jahufer MZZ, Hofmann RW, Anderson CB, Luo D, Ehoche OG, Cousins G, Jones EE, Ballard RA, Griffiths AG.   +9 more
europepmc   +1 more source