Results 161 to 170 of about 7,425,705 (296)

Q&A: Genetic analysis of quantitative traits

Journal of Biology, 2009
Mackay Trudy FC
doaj   +1 more source

Strong amplification of quantitative genetic variation under a balance between mutation and fluctuating stabilizing selection. [PDF]

Genetics
Bertram J, Shafiei Z.
europepmc   +1 more source

The barley mutant multiflorus2.b reveals quantitative genetic variation for new spikelet architecture. [PDF]

Theor Appl Genet, 2022
Koppolu R, Jiang G, Milner SG, Muqaddasi QH, Rutten T, Himmelbach A, Guo Y, Stein N, Mascher M, Schnurbusch T.   +9 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating. [PDF]

Genetics
Krätschmer I, Robinson MR.
europepmc   +1 more source

The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. [PDF]

Proc Natl Acad Sci U S A, 2021
Dugand RJ, Aguirre JD, Hine E, Blows MW, McGuigan K.   +4 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Multivariate trait evolution: models for the evolution of the quantitative genetic <i>G</i>-matrix on phylogenies. [PDF]

Evol Lett
Blomberg SP, Muniz M, Bui MN, Janke C.
europepmc   +1 more source

Hybrid wheat: quantitative genetic parameters and heterosis for quality and rheological traits as well as baking volume. [PDF]

Theor Appl Genet, 2022
Schwarzwälder L, Thorwarth P, Zhao Y, Reif JC, Longin CFH.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source