Results 61 to 70 of about 5,789,434 (312)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Research Center for Quantitative Renal Imaging

open access: yes, 2015
poster abstractMission: The overall mission of the Research Center for Quantitative Renal Imaging is to provide a focused research environment and resource for the development, implementation, and dissemination of innovative, quantitative imaging methods
Research Center for Quantitative Renal Imaging
core   +1 more source

Impact of robotic assistance on the learning curve in endovascular interventions: exploring the role of operator experience with the CorPath GRX system

open access: yesCVIR Endovascular
Purpose This study investigates how endovascular interventionalists adapt to using a robotic platform, specifically the CorPath GRX Robotic System, and examines the influence of prior manual catheterization experience.
Tatjana Dell   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Periarticular cooling reduces non-target perfusion in genicular artery embolization: a quantitative angiographic study

open access: yesCVIR Endovascular
Background Genicular artery embolization (GAE) is an emerging, effective pain treatment for symptomatic knee osteoarthritis. A potential concern of this procedure is non-target embolization of cutaneous and subcutaneous vessels, which can lead to severe ...
Alice M. Jacob   +9 more
doaj   +1 more source

Characterization of the hemodynamic response function in default mode network subregions for task-evoked negative BOLD responses

open access: yesNeuroImage
While the hemodynamic response function (HRF) of the positive blood oxygenated level dependent (BOLD) signal is well characterized in the functional magnetic resonance imaging (fMRI) field, studies investigating the shape and properties of the negative ...
Hengda He   +8 more
doaj   +1 more source

A computer program to assess the bone scan index for Tc-99m hydroxymethylene diphosphonate: evaluation of jaw pathologies of patients with bone metastases using SPECT/CT

open access: yesDiagnostic and Interventional Radiology, 2023
PURPOSEThis study aimed to evaluate the jaw pathologies of patients with bone metastases using a computer program to assess the bone scan index (BSI) for Tc-99m hydroxymethylene diphosphonate (HMDP) with single-photon emission computed tomography ...
Ruri Ogawa, Ichiro Ogura
doaj   +1 more source

Quantitative imaging of chlorophyll fluorescence [PDF]

open access: yesNew Phytologist, 1995
summaryA computer‐controlled video system is described where images of chlorophyll fluorescence from oat (Arena saliva L.) leaves are captured throughout an induction curve. The fluorescence parameters φ11 and ΔFm/F'm which represent photosystem II photochemical efficiency and non‐photochemical quenching respectively are calculated from images taken ...
Stephen A, Rolfe, Julie D, Scholes
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Photon-Counting Micro-CT for Bone Morphometry in Murine Models

open access: yesTomography
Background/Objectives: This study evaluates photon-counting CT (PCCT) for the imaging of mouse femurs and investigates how APOE genotype, sex, and humanized nitric oxide synthase (HN) expression influence bone morphology during aging.
Rohan Nadkarni   +5 more
doaj   +1 more source

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