Results 81 to 90 of about 5,789,434 (312)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Quantitative analysis of retroillumination images [PDF]
We have developed a semi-automated image processing system for analysis and evaluation of retroillumination images. This paper describes methods used to compensate for illumination variations in the images, separation of data into cataractous and non-cataractous portions, how quantitative measurements are made and how they assess the pathological ...
M A, Vivino +4 more
openaire +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Data-driven methods for quantitative imaging [PDF]
In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter.
Dong, G +11 more
core +1 more source
Enhancing Undergraduate Radiography Education Through Quantitative Imaging Research Projects
Applied research and evidence-based practice (EBP) has become part of the core competencies required for the continuous growth of the radiography profession.
Wang, Alan, Mdletshe, Sibusiso
core +1 more source
Quantitative MR Imaging of the Breast
Breast MRI has become essential for diagnosing and managing breast diseases. MRI interpretation has traditionally relied on subjective assessment according to Breast Imaging-Reporting and Data System, but recent advances emphasize the value of quantitative MRI data as objective imaging biomarkers.
Kataoka, Masako +6 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Coins contain multiple types of information, including denomination, design variant, year of issue, and surface condition. This study established a standardized 900–1700 nm short-wave infrared hyperspectral imaging (SWIR-HSI) workflow for controlled and ...
Hsin-Che Wang +6 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

