Results 101 to 110 of about 5,789,434 (312)
HLMiller-Imaging/SlowMembraneDiffusionAnalysis: Version 1
<h2>What's Changed</h2> <ul> <li>Addcode by @HLMiller-Imaging in https://github.com/HLMiller-Imaging/SlowMembraneDiffusionAnalysis/pull/1</li> <li>TrajectoryBugFix by @HLMiller-Imaging in https://github.com/HLMiller ...
HLMiller-Imaging
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Background: Diffusion magnetic resonance imaging (MRI) allows for the quantification of water diffusion properties in soft tissues. The goal of this study was to characterize the 3D collagen fiber network in the porcine meniscus using high angular ...
Zhao, Qi +5 more
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Quantitative musculoskeletal imaging biomarkers [PDF]
Quantitative Imaging in Medicine and Surgery, 2016 “Meten is weten…” (“To measure is to know…”) —Dutch saying In recent decades the importance of quantitative imaging biomarkers has been increasingly recognized, both in research and clinical settings, motivated to a large extent by a growing understanding of the molecular basis of diseases and a need for precision medicine.
openaire +3 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Ultrasonic Imaging and Quantitative Nondestructive Evaluation of the Hearts of Patients [PDF]
, 1995 Cross fertilization between the quantitative nondestructive evaluation (QNDE) community and the diagnostic medicine community in the area of ultrasonics represents an attractive but challenging goal.
Mark R. Holland +9 more
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Frontiers in Biomedical Technologies, 2019 Purpose: The purpose of this study is to evaluate the brain alterations in epileptic patients and normal adults in order to help differential diagnosis using volumetric Magnetic Resonance Imaging (MRI).
Hanieh Mobarak Salari +5 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Imaging of body composition in children.
Overweight and obesity in children and adolescents have become a worldwide public health concern with an ever-increasing prevalence. An excessive accumulation of intraabdominal fat tissue increases the risk of developing insulin resistance, diabetes, and
Guglielmi, Riccardo +2 more
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