Results 91 to 100 of about 36,219,545 (383)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Combining healthiness and sustainability: An analysis of consumers’ preferences and willingness to pay for functional and sustainable snack bars

Future Foods
Despite the growing attention paid by consumers and policy makers to health and sustainability issues, contribution analyzing consumers attitude towards both health related and sustainability attributes of foods are lacking.
Anna Uliano, Marcello Stanco, Giuseppe Marotta, Concetta Nazzaro   +3 more
doaj   +1 more source

Joinpoint regression analysis with time-on-study as time-scale. Application to three Italian population-based cohort studies

Epidemiology, Biostatistics and Public Health, 2017
Background: Joinpoint regression analysis is usually applied to study varying trends over time in order to identify the time point(s) in which the trend significantly changes.
Eleonora Pagan, Federico Rea, Matteo Monzio Compagnoni, Anna Cantarutti, Pietro Pugni, Vincenzo Bagnardi, Giovanni Corrao   +6 more
doaj   +1 more source

Methods and Techniques for Quali-Quantitative Analyses: an Agricultural Application [PDF]

[En] This paper describes a dynamic systems model which links the private and public functions of agriculture with the territorial development of rural regions and quality of life of rural residents.
Maria Giuseppina Eboli
core  

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

The Dynamic Window Approach as a Tool to Improve Performance of Nonparametric Self-Starting Control Charts

Mathematics
The change-point model is an established methodology for the construction of self-starting control charts. Change-point charts are often nonparametric in order to be independent from any specific assumptions about the process distribution.
Claudio Giovanni Borroni, Manuela Cazzaro, Paola Maddalena Chiodini   +2 more
doaj   +1 more source

Key performance indicators for factor score based ranking in One Day International cricket

IIMB Management Review, 2020
Player rankings are of concern to sports authorities, players and sports enthusiasts, and with commercialisation of sports, rankings are even more important to investors.
Prashant Premkumar, Jimut Bahan Chakrabarty, Shovan Chowdhury   +2 more
doaj   +1 more source

Beam-modulation methods in quantitative and flow visualization holographic interferometry [PDF]

This report discusses heterodyne holographic interferometry and time-average holography with a frequency shifted reference beam. Both methods will be used for the measurement and visualization of internal transonic flows, where the target facility is a ...
Decker, A.
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Factors Influencing User Perception and Adoption of E-Government Services

Administrative Sciences
The objective of this study is to investigate and determine factors influencing user perception and acceptance of electronic government services in the context of technological advancements.
Galina Ilieva, Tania Yankova, Margarita Ruseva, Yulia Dzhabarova, Veselina Zhekova, Stanislava Klisarova-Belcheva, Tanya Mollova, Angel Dimitrov   +7 more
doaj   +1 more source