Results 231 to 240 of about 36,219,545 (383)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

One of the major challenges of masking the bitter taste in medications: an overview of quantitative methods for bitterness. [PDF]

Front Chem
Wang P, Li H, Wang Y, Dong F, Li H, Gui X, Ren Y, Gao X, Li X, Liu R.   +9 more
europepmc   +1 more source

Framework for Patient Experience Value Elements in Rare Disease: A Case Study Demonstrating the Applicability of Combined Qualitative and Quantitative Methods. [PDF]

Pharmacoecon Open, 2023
McQueen RB, Mendola ND, Jakab I, Bennett J, Nair KV, Németh B, Inotai A, Kaló Z.   +7 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Assessing non-invasive quantitative methods for [¹⁸F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain. [PDF]

Eur J Nucl Med Mol Imaging
Berckmans L, Schrauwen C, Miranda A, Staelens S, Bertoglio D.   +4 more
europepmc   +1 more source

Quantitative methods and modeling to assess COVID-19-interrupted in vivo pharmacokinetic bioequivalence studies with two reference batches. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2022
Gong Y, Feng K, Zhang P, Lee J, Pan Y, Zhang Z, Ni Z, Bai T, Yoon M, Li B, Kim CY, Fang L, Zhao L.   +12 more
europepmc   +1 more source

The Application of a Quantitative Complement-Fixation Method to a Study of Q Fever Strain Differentiation [PDF]

, 1949
Don M. Wolfe, Lottie Kornfeld
openalex   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Evaluation of Local Tumor Outcomes Following Microwave Ablation of Colorectal Liver Metastases Using CT Imaging: A Comparison of Visual versus Quantitative Methods. [PDF]

Radiol Imaging Cancer
Shur JD, Porta N, Kafaei L, Pendower L, McCall J, Khan N, Oyen W, Koh DM, Johnston E.   +8 more
europepmc   +1 more source

Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity - from single-cell to spatial omic methods. [PDF]

Biophys Rev, 2022
Ho JWK, Chen X, He M, Huang Y, Mar JC, Shih DJH, Wu AR.   +6 more
europepmc   +1 more source