Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks
Abstract Objective Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. Methods We performed a retrospective study of patients with NMOSD based on the Wingerchuk 2006 or the revised Wingerchuk 2015 criteria ...
Qin Du+7 more
wiley +1 more source
One of the major challenges of masking the bitter taste in medications: an overview of quantitative methods for bitterness. [PDF]
Wang P+9 more
europepmc +1 more source
Quantitative methods to study helicase, DNA polymerase, and exonuclease coupling during DNA replication. [PDF]
Singh A, Patel SS.
europepmc +1 more source
A QUANTITATIVE METHOD OF DETERMINING THE LETHAL EFFECT OF ULTRAVIOLET LIGHT ON BACTERIA SUSPENDED IN AIR [PDF]
D. G. Sharp
openalex +1 more source
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Quantitative methods for optimizing patient outcomes in liver transplantation. [PDF]
Al-Bahou R+3 more
europepmc +1 more source
Quantitative methods and modeling to assess COVID-19-interrupted in vivo pharmacokinetic bioequivalence studies with two reference batches. [PDF]
Gong Y+12 more
europepmc +1 more source