Results 91 to 100 of about 1,382,288 (265)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

How ESG corporate reputation affects sustainability premiums in the insurance industry

Frontiers in Applied Mathematics and Statistics
Based on increasing ESG awareness, executives, and investment professionals consider ESG factors in strategic and operational decisions. Like other companies, insurers recognize that the ESG transition offers opportunities for long-term value creation ...
Maria Carannante, Valeria D'Amato, Maria Sole Staffa   +2 more
doaj   +1 more source

Quantitative recognition method for borehole trajectory models

Petroleum Exploration and Development, 2018
In order to accurately calculate drilled trajectories, the method of quantitatively recognizing borehole trajectory models was provided, and a case analysis was conducted.
Xiushan LIU
doaj   +1 more source

Quantitative models for building and growing fated small cell networks. [PDF]

Interface Focus, 2022
Diegmiller R, Nunley H, Shvartsman SY, Imran Alsous J.   +3 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A literature review on quantitative models for supply chain risk management: Can they be applied to pandemic disruptions? [PDF]

Comput Ind Eng, 2022
Rinaldi M, Murino T, Gebennini E, Morea D, Bottani E.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Recent applications of chaos theory in medical sciences: progress and challenges

BMC Biomedical Engineering
Background The application of chaos theory has positive results in different fields of science. Its nonlinear modeling properties and its vision of dynamic systems have enabled it to capture complex relationships in fields such as physics, financial ...
Oscar Espinosa, Angélica Ordóñez, Gabriela Puentes   +2 more
doaj   +1 more source

Predictive modelling of the effectiveness of vaccines against COVID-19 in Bogotá: Methodological innovation involving different variants and computational optimisation efficiency

Heliyon
The uncertainty associated with the future of viruses such as SARS-CoV-2 poses a challenge to public health officials because of its implications for welfare, economics and population health. In this document, we develop an age-stratified epidemiological-
Oscar Espinosa, Lisa White, Valeria Bejarano, Ricardo Aguas, Duván Rincón, Laura Mora, Antonio Ramos, Cristian Sanabria, Jhonathan Rodríguez, Nicolás Barrera, Carlos Álvarez-Moreno, Jorge Cortés, Carlos Saavedra, Adriana Robayo, Bo Gao, Oscar Franco   +15 more
doaj   +1 more source

Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose-Response Inference on hERG Inhibition Models. [PDF]

Int J Mol Sci, 2022
Melnikov F, Anger LT, Hasselgren C.
europepmc   +1 more source