Results 41 to 50 of about 1,313,775 (264)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Health Economics ReviewIn Colombia, health expenditure is highly concentrated, with a small portion of the population incurring most costs, particularly in rural areas. Men show greater inequality than women.
Oscar Espinosa +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A new tool to detect financial data scaling
Frontiers in Applied Mathematics and StatisticsThe assumption of frictionless markets has long been debated, drawing interest from scholars and practitioners alike. Market liquidity is a central theme in this regard; it is traditionally assessed through transaction costs, volume, price-based, and ...
Sergio Bianchi +3 more
doaj +1 more source
QuantUM: Quantitative Safety Analysis of UML Models [PDF]
Electronic Proceedings in Theoretical Computer Science, 2011 When developing a safety-critical system it is essential to obtain an assessment of different design alternatives. In particular, an early safety assessment of the architectural design of a system is desirable.
Florian Leitner-Fischer, Stefan Leue
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Analysing the Physical and Spatial Expansion Pattern of Margheh Using Quantatitive Models [PDF]
نشریه جغرافیا و برنامهریزی, 2013 The growth and development pattern or city form is defined as spatial pattern of human activities. At present the city pattern is divided into two groups as horizontal or sprawl and vertical or compact.
Sedigheh Lotfi +2 more
doaj
From quantitative SBML models to Boolean networks
Applied Network Science, 2022 Modelling complex biological systems is necessary for their study and understanding. Biomodels is a repository of peer-reviewed models represented in the Systems Biology Markup Language (SBML).
Athénaïs Vaginay +2 more
doaj +1 more source
Quantitative reactive modeling and verification [PDF]
Computer Science - Research and Development, 2013 Formal verification aims to improve the quality of software by detecting errors before they do harm. At the basis of formal verification is the logical notion of correctness, which purports to capture whether or not a program behaves as desired. We suggest that the boolean partition of software into correct and incorrect programs falls short of the ...
Henzinger, Thomas A
openaire +2 more sources