Results 201 to 210 of about 222,034 (259)

Quantitative MRI Characterization of Fluid-Related Phenotypes in Pediatric Epilepsy: Deep Learning-Assisted Assessment of Enlarged Perivascular Space Burden, Regional Distribution, and Clinical Associations. [PDF]

Diagnostics (Basel)
Aytaç A, Aydın H.
europepmc   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent. [PDF]

Theranostics
Mohanta Z, Tressler CM, Gori S, Singh A, Stabinska J, Bo S, Karbalaei S, Sall S, Gilad A, Bertoni HL, Gale E, Glunde K, McMahon MT.   +12 more
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Beyond iron concentration: iron aggregation shapes quantitative MRI in the human brain

Stürz A, Panzer M, Glodny B, Gizewski ER, Zoller H, Birkl C.   +5 more
europepmc   +1 more source

Textural Features from Quantitative MRI Using T2 Relaxation Times Correlate with Histological Cartilage Degeneration: An Ex-Vivo Study. [PDF]

Cartilage
Schreiner M, Toegel S, Janacova V, Szomolanyi P, Laurent D, Saxer F, Schieker M, Heule R, Bieri O, Raithel E, Fuchssteiner C, Weninger WJ, Windhager R, Trattnig S, Hager B, Juras V.   +15 more
europepmc   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

Association of knee osseous morphometric parameters with degeneration and tear of the discoid lateral meniscus: a cross-sectional quantitative MRI study. [PDF]

Quant Imaging Med Surg
Ali S, Zeng W, Li H, Chen X, Tang Z, Liu Q, Pu Y, Jin Y, Fang W, Yang H.   +9 more
europepmc   +1 more source

Quantitative MRI assessment of left ventricular filling: associations with left atrial and pulmonary artery dimensions in a population-based study. [PDF]

Front Cardiovasc Med
Wintergerst C, Lorbeer R, Rospleszcz S, Askani E, Mujaj B, Bulwer BE, Peters A, Schulz H, Schlett CL, Bamberg F, von Krüchten R.   +10 more
europepmc   +1 more source

Platelet-Rich Plasma (PRP) Assessment in Degenerative Discovertebral Complexes (DVC) Using Quantitative MRI at 4.7T: A Preliminary Animal In Vivo Study. [PDF]

Bioengineering (Basel)
Dallaudière B, Ribot EJ, Dallet L, Trotier AJ, Thibaudeau O, Miraux S, Hauger O.   +6 more
europepmc   +1 more source