Results 121 to 130 of about 27,786,773 (306)

Quantitative analysis by HPLC-MS2 of the pyrrolizidine alkaloid adonifoline in Senecio scandens

, 2008
A quantitative method using HPLC-MS2 has been developed for the determination of adonifoline, one of the retronecine-type hepatotoxic pyrrolizidine alkaloids in Senecio scandens Buch.-Ham. ex D. Don., a traditional Chinese herb.
Wang, C.-H., Zhang, F., Ma, H.Y., Wang, W., Zhang, M., Wang, Z., Bligh, S.W.A., Zhang, C.-F., Chen, L.X.   +8 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Investigation Phase: Quantitative Analysis of Domain Ontology Usage (QUA-AF)

, 2018
© 2018, Springer International Publishing AG, part of Springer Nature. In the previous chapter, the EMP-AF was proposed to perform an empirical analysis of domain ontology usage.
Hussain, FK, Farookh Khadeer Hussain, Elizabeth J. Chang, Ashraf, J, Jamshaid Ashraf, Hussain, OK, Chang, EJ, Omar K. Hussain   +7 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Tomographic microscope for low-coherent quantitative phase imaging

A novel tomographic microscope setup utilizing the principle of Holographic Incoherent-light-source Quantitative Phase Imaging is introduced. This setup combines the advantages of achromatic off-axis holography with the ultrafast operation of a digital ...
Buček, Jozef, Špaček, Matěj, Pachl, Přemysl, Dvořák, Vladislav, Dostál, Zbyněk, Neumanová, Anna   +5 more
core   +1 more source

On-site quantitative analysis of As(III) and As(V) in aqueous phase using portable laser-induced fluorescence platform

Communications Engineering
Arsenic contaminants exist in different chemical forms with varying toxicity and mobility, making on-site analysis challenging. Here, a fluorogenic method is developed for the efficient detection of arsenite and arsenate ions using a portable platform ...
Lixia Feng, Qilong Bian, Shujun Wu, Tianyu Gao, Pei Zhang, Shujian Dai, Zebing Zeng, Sheng Xie   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Quantitative X-ray mapping, scatter diagrams and the generation of correction maps to obtain more information about your material

, 2014
Quantitative X-ray mapping with silicon drift detectors and multi-EDS detector systems have become an invaluable analysis technique and one of the most useful methods of X-ray microanalysis today. The time to perform an X-ray map has reduced considerably
Moran, Ken, Wuhrer, Richard (R17216)
core