Results 41 to 50 of about 659,328 (290)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Assessing College Students’ Quantitative and Scientific Reasoning: The James Madison University Story

open access: yesNumeracy, 2015
Quantitative and scientific reasoning is a critical student learning outcome in higher education. Data are presented for large samples of undergraduate students who were assessed as entering freshmen and then again after completing 45-70 credit hours ...
John D. Hathcoat   +2 more
doaj   +1 more source

Quantitative Logic Reasoning [PDF]

open access: yes, 2018
Appeared as a chapter in Trends in Logic ...
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Review of Math for Life by Jeffrey Bennett

open access: yesNumeracy, 2012
Math for Life: Crucial Ideas You Didn’t Learn in School by Jeffrey Bennett is a general interest mathematics book focused on the topic of innumeracy, the mathematics required to be numerate and why quantitative literacy is important for an educated ...
Eric Gaze
doaj   +1 more source

Quantitative Reasoning Learning Progression: The Matrix

open access: yesNumeracy, 2014
The NSF Pathways Project studied the development of environmental literacy in students from grades six through high school. Learning progressions for environmental literacy were developed to explicate the trajectory of learning.
Robert L. Mayes   +4 more
doaj   +1 more source

Parts of the Whole: The Last Column: Freire's Pedagogy of Liberation

open access: yesNumeracy, 2020
The educational theory of Paolo Freire is briefly summarized for instructors of quantitative reasoning, with a focus on what it means to give students “agency.” Some examples are given of how to implement his basic ideas.
Dorothy Wallace
doaj   +1 more source

Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning [PDF]

open access: yes, 2018
Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations.
Colloc, Joël   +4 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Quantitative Reasoning Learning Progressions for Environmental Science: Developing a Framework

open access: yesNumeracy, 2013
Quantitative reasoning is a complex concept with many definitions and a diverse account in the literature. The purpose of this article is to establish a working definition of quantitative reasoning within the context of science, construct a quantitative ...
Robert L. Mayes   +2 more
doaj   +1 more source

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