Results 51 to 60 of about 72,973 (263)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Quantitative Examination of Explanations for Reasons for Internet Nonuse [PDF]

open access: yesCyberpsychology, Behavior, and Social Networking, 2013
This article investigates patterns of reasons for digital disengagement of British adults. It adds a psychological dimension to research that is mostly sociological in nature in trying to separate out explanations for disengaging from the Internet by choice or by forced exclusion.
Ellen J. Helsper, Bianca C. Reisdorf
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Management education in the age of information overload [PDF]

open access: yesOrganization Management Journal
Purpose – The purpose of this paper is to advocate for the integration of quantitative reasoning into management education and leadership development literature.
Kenneth Michael Sweet   +2 more
doaj   +1 more source

4 Quantitative Reasoning and the Development of Algebraic Reasoning [PDF]

open access: yes, 2017
Recent discussions of algebra reform have focused on having more students take algebra courses and on improving their mathematical content. We believe that neither approach can be successful without substantial changes in the K-8 mathematics curriculum's current focus on numbers and arithmetic operations.
John P. Jack, Patrick W. Thompson
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A Comparison of Students’ Quantitative Reasoning Skills in STEM and Non-STEM Math Pathways

open access: yesNumeracy, 2020
Quantitative Reasoning (QR) is essential for today’s students, yet most higher education institutions have not effectively addressed this issue. This study investigates students’ quantitative reasoning in STEM and Non-STEM math pathways using a non ...
Emily Elrod, Joo Young Park
doaj   +1 more source

On Quantifiers for Quantitative Reasoning

open access: yesCoRR
We explore a kind of first-order predicate logic with intended semantics in the reals. Compared to other approaches in the literature, we work predominantly in the multiplicative reals $[0,\infty]$, showing they support three generations of connectives, that we call non-linear, linear additive, and linear multiplicative. Means and harmonic means emerge
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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